Perioperative stroke is a potentially devastating complication in patients undergoing
noncardiac, nonneurological surgery. This scientific statement summarizes established risk …

Background There are very few patient-centred global outcome measures of recovery in the
days or weeks after surgery. This meta-analysis evaluated the psychometric properties and …

Background Postoperative delirium is a serious complication of surgery associated with
prolonged hospitalisation, long-term cognitive decline, and mortality. This study aimed to …

Background Early recognition and management of postoperative complications, before they
become clinically relevant, can improve postoperative outcomes for patients, especially for …

Background 'Depth of anaesthesia'monitors claim to measure hypnotic depth during general
anaesthesia from the EEG, and clinicians could reasonably expect agreement between …

Background Target-controlled infusion (TCI) systems incorporating pharmacokinetic (PK) or
PK-pharmacodynamic (PK-PD) models can be used to facilitate drug administration. Existing …

Background Postoperative delirium (POD) is the most common serious postoperative
complication in older adults. It has uncertain aetiology, limited preventative strategies, and …

Enhanced perioperative care protocols become the standard of care in elective surgery with
a significant improvement in patients' outcome. The key element of the enhanced …

Background Remimazolam tosilate (RT) is a novel short-acting GABA (A) receptor agonist
that has a rapid recovery from procedural sedation and can be fully reversed by flumazenil …

Study objective In the upcoming years there will be a growing number of elderly patients
requiring general anaesthesia. As age is an independent risk factor for postoperative …