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One-pot chemo-and photo-enzymatic linear cascade processes
JM Carceller, KS Arias, MJ Climent, S Iborra… - Chemical Society …, 2024 - pubs.rsc.org
The combination of chemo-and photocatalyses with biocatalysis, which couples the flexible
reactivity of the photo-and chemocatalysts with the highly selective and environmentally …
reactivity of the photo-and chemocatalysts with the highly selective and environmentally …
Resource utilization of carbon dioxide and nitrate to produce value-added organonitrogen compounds through an electrochemical approach
K Yu, H Wang, W Yu, S Li, X Zhang, Z Bian - Applied Catalysis B …, 2024 - Elsevier
Excess CO 2 and NO 3-released by human industrial activities have contributed to the
deterioration of the global environment. Simultaneous activation and reduction of CO 2 and …
deterioration of the global environment. Simultaneous activation and reduction of CO 2 and …
Combinatorial gene inactivation of aldehyde dehydrogenases mitigates aldehyde oxidation catalyzed by E. coli resting cells
Aldehydes are attractive chemical targets both as end products in the flavors and fragrances
industry and as synthetic intermediates due to their propensity for C–C bond formation …
industry and as synthetic intermediates due to their propensity for C–C bond formation …
Selective biocatalytic defunctionalization of raw materials
R Wohlgemuth - ChemSusChem, 2022 - Wiley Online Library
Biobased raw materials, such as carbohydrates, amino acids, nucleotides, or lipids contain
valuable functional groups with oxygen and nitrogen atoms. An abundance of many …
valuable functional groups with oxygen and nitrogen atoms. An abundance of many …
Engineered aldoxime dehydratase to enable the chemoenzymatic conversion of benzyl amines to aromatic nitriles
Q **ao, Y Feng, L Chen, M Li, P Zhang, Q Wang… - Bioorganic …, 2023 - Elsevier
A chemoenzymatic strategy has been implemented to synthesize nitriles from benzyl amines
under mild conditions. Aldoxime dehydratase (Oxd) plays a decisive role to convert …
under mild conditions. Aldoxime dehydratase (Oxd) plays a decisive role to convert …
Biocatalytic carboxylate reduction–recent advances and new enzymes
Carboxylate reductases (CARs) are valuable catalysts for the selective one‐step reduction
of carboxylic acids to their corresponding aldehydes. In recent years, numerous new CARs …
of carboxylic acids to their corresponding aldehydes. In recent years, numerous new CARs …
Organic acid to nitrile: a chemoenzymatic three‐step route
M Winkler, M Horvat, A Schiefer… - Advanced Synthesis …, 2023 - Wiley Online Library
Various widely applied compounds contain cyano‐groups, and this functional group serves
as a chemical handle for a whole range of different reactions. We report a cyanide free …
as a chemical handle for a whole range of different reactions. We report a cyanide free …
Scanning aldoxime dehydratase sequence space and characterization of a new aldoxime dehydratase from Fusarium vanettenii
B Křístková, R Rädisch, N Kulik, M Horvat… - Enzyme and Microbial …, 2023 - Elsevier
The aim of this work was to map the sequence space of aldoxime dehydratases (Oxds) as
enzymes with great potential for nitrile synthesis. Microbes contain an abundance of putative …
enzymes with great potential for nitrile synthesis. Microbes contain an abundance of putative …
Programing a cyanide-free transformation of aldehydes to nitriles and one-pot synthesis of amides through tandem chemo-enzymatic cascades
H Zheng, Q **ao, F Mao, A Wang, M Li, Q Wang… - RSC …, 2022 - pubs.rsc.org
Nitriles are broadly applied to synthesize pharmaceuticals, agrochemicals, and materials
because of their versatile transformation. Although various methods have been developed …
because of their versatile transformation. Although various methods have been developed …
Enzymatic properties of a non-classical aldoxime dehydratase capable of producing alkyl and arylalkyl nitriles
X Pei, Q **ao, Y Feng, L Chen, F Yang, Q Wang… - Applied Microbiology …, 2023 - Springer
Nitriles are of significant interest in the flavor and fragrance industries with potential
application in cosmetics due to their higher stability than analogous aldehydes. However …
application in cosmetics due to their higher stability than analogous aldehydes. However …