Current understanding of the molecular and cellular pathology of diabetic retinopathy
Diabetes mellitus has profound effects on multiple organ systems; however, the loss of
vision caused by diabetic retinopathy might be one of the most impactful in a patient's life …
vision caused by diabetic retinopathy might be one of the most impactful in a patient's life …
Molecular genetics and emerging therapies for retinitis pigmentosa: Basic research and clinical perspectives
MF Dias, K Joo, JA Kemp, SL Fialho… - Progress in retinal and …, 2018 - Elsevier
Retinitis Pigmentosa (RP) is a hereditary retinopathy that affects about 2.5 million people
worldwide. It is characterized with progressive loss of rods and cones and causes severe …
worldwide. It is characterized with progressive loss of rods and cones and causes severe …
Vision loss after intravitreal injection of autologous “stem cells” for AMD
AE Kuriyan, TA Albini, JH Townsend… - … England Journal of …, 2017 - Mass Medical Soc
Adipose tissue–derived “stem cells” have been increasingly used by “stem-cell clinics” in the
United States and elsewhere to treat a variety of disorders. We evaluated three patients in …
United States and elsewhere to treat a variety of disorders. We evaluated three patients in …
[HTML][HTML] Retinal stem cell transplantation: Balancing safety and potential
Stem cell transplantation holds great promise as a potential treatment for currently incurable
retinal degenerative diseases that cause poor vision and blindness. Recently, safety data …
retinal degenerative diseases that cause poor vision and blindness. Recently, safety data …
[HTML][HTML] Stemming retinal regeneration with pluripotent stem cells
ZB **, ML Gao, WL Deng, KC Wu, S Sugita… - Progress in retinal and …, 2019 - Elsevier
Cell replacement therapy is a promising treatment for irreversible retinal cell death in diverse
diseases, such as age-related macular degeneration (AMD), Stargardt's disease, retinitis …
diseases, such as age-related macular degeneration (AMD), Stargardt's disease, retinitis …
Regenerating eye tissues to preserve and restore vision
Ocular regenerative therapies are on track to revolutionize treatment of numerous blinding
disorders, including corneal disease, cataract, glaucoma, retinitis pigmentosa, and age …
disorders, including corneal disease, cataract, glaucoma, retinitis pigmentosa, and age …
Retinitis pigmentosa: progress in molecular pathology and biotherapeutical strategies
W Liu, S Liu, P Li, K Yao - International Journal of Molecular Sciences, 2022 - mdpi.com
Retinitis pigmentosa (RP) is genetically heterogeneous retinopathy caused by
photoreceptor cell death and retinal pigment epithelial atrophy that eventually results in …
photoreceptor cell death and retinal pigment epithelial atrophy that eventually results in …
Bioengineering strategies for restoring vision
Late-stage retinal degenerative disease involving photoreceptor loss can be treated by
optogenetic therapy, cell transplantation and retinal prostheses. These approaches aim to …
optogenetic therapy, cell transplantation and retinal prostheses. These approaches aim to …
[HTML][HTML] Stem cell treatment of degenerative eye disease
Stem cell therapies are being explored extensively as treatments for degenerative eye
disease, either for replacing lost neurons, restoring neural circuits or, based on more recent …
disease, either for replacing lost neurons, restoring neural circuits or, based on more recent …
Review of adaptive optics OCT (AO-OCT): principles and applications for retinal imaging
In vivo imaging of the human retina with a resolution that allows visualization of cellular
structures has proven to be essential to broaden our knowledge about the physiology of this …
structures has proven to be essential to broaden our knowledge about the physiology of this …