Mitochondria are key intracellular organelles involved not only in the metabolic state of the
cell, but also in several cellular functions, such as proliferation, Calcium signaling, and lipid …

Central nervous system (CNS) diseases are among the most difficult to treat, mainly
because the vast majority of the drugs fail to cross the blood-brain barrier (BBB) or to reach …

Mitochondria provide chemical energy for endoergonic reactions in the form of ATP, and
their activity must meet cellular energy requirements, but the mechanisms that link organelle …

Background Cardamonin, a chalcone isolated from Alpiniae katsumadai, has anti-
inflammatory and anti-tumor activities. However, the molecular mechanism by which …

Mitochondrial metabolism has emerged as a promising target against the mechanisms of
tumor growth. Herein, we have screened an FDA-approved library to identify drugs that …

Potassium (K+) channels are highly regulated membrane proteins that control the potassium
ion flux and respond to different cellular stimuli. These ion channels are grouped into three …

Simple Summary Although there are various treatments for tumors, chemotherapy is still one
of the most dominant and irreplaceable treatment modalities nowadays. Unfortunately …

The aim of this study was to prepare Cinnamomum cassia essential oil (CEO) impregnated
chitosan nanoparticles (CS-CEO) and assess its pharmacological activity against breast …

Cancer chemoprevention is the most effective approach to control cancer in the population.
Despite significant progress, chemoprevention has not been widely adopted because …

Mitochondria are vital to life and provide biological energy for other organelles and cell
physiological processes. On the mitochondrial double layer membrane, there are a variety of …