Pathogenesis and genetics of pre-eclampsia

JM Roberts, DW Cooper - The Lancet, 2001 - thelancet.com
After more than a century of intensive research, pre-eclampsia and eclampsia remain an
enigmatic set of conditions. Aberration of the interaction between placental and maternal …

Preeclampsia: recent insights

JM Roberts, HS Gammill - Hypertension, 2005 - Am Heart Assoc
Preeclampsia is a pregnancy complication with serious consequences for mother and infant.
The disorder is diagnosed by gestational hypertension and proteinuria but is far more than …

The nature of nurture: Effects of parental genotypes

A Kong, G Thorleifsson, ML Frigge, BJ Vilhjalmsson… - Science, 2018 - science.org
Sequence variants in the parental genomes that are not transmitted to a child (the proband)
are often ignored in genetic studies. Here we show that nontransmitted alleles can affect a …

[BOOK][B] The kidney

BM Brenner, FC Rector - 1976 - books.google.com
Page 1 0349-4 Supreme Court Appellate term SSOCIATION OF THE BAR с CITY OF NE
YORK 1928 Vol 25 October Term Page 2 DEC 28 1928 155454 Page 3 766 New York …

Selection against variants in the genome associated with educational attainment

A Kong, ML Frigge, G Thorleifsson… - Proceedings of the …, 2017 - National Acad Sciences
Epidemiological and genetic association studies show that genetics play an important role in
the attainment of education. Here, we investigate the effect of this genetic component on the …

[HTML][HTML] Preeclampsia: a renal perspective

SA Karumanchi, SE Maynard, IE Stillman, FH Epstein… - Kidney international, 2005 - Elsevier
Preeclampsia: A renal perspective. Preeclampsia is a syndrome that affects 5% of all
pregnancies, producing substantial maternal and perinatal morbidity and mortality. The aim …

Genomewide scans of complex human diseases: true linkage is hard to find

J Altmüller, LJ Palmer, G Fischer, H Scherb… - The American Journal of …, 2001 - cell.com
Many" complex" human diseases, which involve multiple genetic and environmental
determinants, have increased in incidence during the past 2 decades. During the same time …

[HTML][HTML] The genetics of pre-eclampsia and other hypertensive disorders of pregnancy

PJ Williams, FB Pipkin - Best practice & research Clinical obstetrics & …, 2011 - Elsevier
Hypertension is the most frequent medical complication occurring during pregnancy. In this
chapter, we aim to address the genetic contribution to these disorders, with specific focus on …

Mechanisms of disease: pre-eclampsia

M Noris, N Perico, G Remuzzi - Nature clinical practice Nephrology, 2005 - nature.com
Pre-eclampsia, a syndrome of pregnant women, is one of the leading causes of maternal
and fetal morbidity and mortality. Despite active research, the etiology of this disorder …

Preeclampsia and angiogenic imbalance

S Maynard, FH Epstein, SA Karumanchi - Annu. Rev. Med., 2008 - annualreviews.org
Preeclampsia is a systemic syndrome of pregnancy that originates in the placenta and is
characterized by widespread maternal endothelial dysfunction. Until recently, the molecular …