The role of the PI3K/AKT signalling pathway in the corneal epithelium: recent updates
K Chen, Y Li, X Zhang, R Ullah, J Tong, Y Shen - Cell death & disease, 2022 - nature.com
Abstract Phosphatidylinositol 3 kinase (PI3K)/AKT (also called protein kinase B, PKB)
signalling regulates various cellular processes, such as apoptosis, cell proliferation, the cell …
signalling regulates various cellular processes, such as apoptosis, cell proliferation, the cell …
Functional carbon quantum dots for ocular imaging and therapeutic applications
Carbon quantum dots (CDs) are a class of emerging carbonaceous nanomaterials that have
received considerable attention due to their excellent fluorescent properties, extremely small …
received considerable attention due to their excellent fluorescent properties, extremely small …
Super-cationic carbon quantum dots synthesized from spermidine as an eye drop formulation for topical treatment of bacterial keratitis
We have developed a one-step method to synthesize carbon quantum dots (CQDPAs) from
biogenic polyamines (PAs) as an antibacterial agent for topical treatment of bacterial …
biogenic polyamines (PAs) as an antibacterial agent for topical treatment of bacterial …
An ocular commensal protects against corneal infection by driving an interleukin-17 response from mucosal γδ T cells
Mucosal sites such as the intestine, oral cavity, nasopharynx, and vagina all have
associated commensal flora. The surface of the eye is also a mucosal site, but proof of a …
associated commensal flora. The surface of the eye is also a mucosal site, but proof of a …
Niosomal drug delivery systems for ocular disease—Recent advances and future prospects
The eye is a complex organ consisting of several protective barriers and particular defense
mechanisms. Since this organ is exposed to various infections, genetic disorders, and visual …
mechanisms. Since this organ is exposed to various infections, genetic disorders, and visual …
Next-generation nanomaterials: advancing ocular anti-inflammatory drug therapy
J Wei, J Mu, Y Tang, D Qin, J Duan, A Wu - Journal of nanobiotechnology, 2023 - Springer
Ophthalmic inflammatory diseases, including conjunctivitis, keratitis, uveitis, scleritis, and
related conditions, pose considerable challenges to effective management and treatment …
related conditions, pose considerable challenges to effective management and treatment …
Innate immune system activation, inflammation and corneal wound healing
N Fortingo, S Melnyk, SH Sutton, MA Watsky… - International journal of …, 2022 - mdpi.com
Corneal wounds resulting from injury, surgeries, or other intrusions not only cause pain, but
also can predispose an individual to infection. While some inflammation may be beneficial to …
also can predispose an individual to infection. While some inflammation may be beneficial to …
Antimicrobial carbon materials-based quantum dots: From synthesis strategies to antibacterial properties for diagnostic and therapeutic applications in wound healing
The emergence of multidrug resistance (MDR) pathogens and the rapid depletion of the
antibiotic arsenal have sparked interest in discovering and develo** innovative …
antibiotic arsenal have sparked interest in discovering and develo** innovative …
Carbonized nanogels for simultaneous antibacterial and antioxidant treatment of bacterial keratitis
To prevent visual loss, clinical therapy of severe bacterial keratitis (BK) demands
simultaneous remedying of the damage caused by bacterial infection and its induced …
simultaneous remedying of the damage caused by bacterial infection and its induced …
Ferrous sulfate-loaded hydrogel cures Staphylococcus aureus infection via facilitating a ferroptosis-like bacterial cell death in a mouse keratitis model
Hydrogels loaded with ampicillin, vancomycin or other antibiotics are one of the most widely
used therapeutic agents for keratitis caused by Staphylococcus aureus. However …
used therapeutic agents for keratitis caused by Staphylococcus aureus. However …