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[HTML][HTML] The 2021 WHO classification of lung tumors: impact of advances since 2015
AG Nicholson, MS Tsao, MB Beasley… - Journal of Thoracic …, 2022 - Elsevier
Abstract The 2021 WHO Classification of Thoracic Tumours was published earlier this year,
with classification of lung tumors being one of the chapters. The principles remain those of …
with classification of lung tumors being one of the chapters. The principles remain those of …
Challenge and countermeasures for EGFR targeted therapy in non-small cell lung cancer
Lung cancer causes the highest mortality compared to other cancers in the world according
to the latest WHO reports. Non-small cell lung cancer (NSCLC) contributes about 85% of …
to the latest WHO reports. Non-small cell lung cancer (NSCLC) contributes about 85% of …
Sintilimab plus chemotherapy for patients with EGFR-mutated non-squamous non-small-cell lung cancer with disease progression after EGFR tyrosine-kinase inhibitor …
S Lu, L Wu, H Jian, Y Cheng, Q Wang… - The Lancet …, 2023 - thelancet.com
Background In the first interim analysis of the ORIENT-31 trial, compared with chemotherapy
alone, sintilimab plus bevacizumab biosimilar IBI305 plus chemotherapy (pemetrexed and …
alone, sintilimab plus bevacizumab biosimilar IBI305 plus chemotherapy (pemetrexed and …
Five-year overall survival for patients with advanced non‒small-cell lung cancer treated with pembrolizumab: results from the phase I KEYNOTE-001 study
PURPOSE Pembrolizumab monotherapy has demonstrated durable antitumor activity in
advanced programmed death ligand 1 (PD-L1)–expressing non‒small-cell lung cancer …
advanced programmed death ligand 1 (PD-L1)–expressing non‒small-cell lung cancer …
Lung cancer in never smokers—the East Asian experience
F Zhou, C Zhou - Translational lung cancer research, 2018 - pmc.ncbi.nlm.nih.gov
Approximately one third of all lung cancer patients in East Asia are never-smokers.
Furthermore, the proportion of lung cancer in never smokers (LCINS) has been increasing …
Furthermore, the proportion of lung cancer in never smokers (LCINS) has been increasing …
Nonsmall cell lung carcinoma: Diagnostic difficulties in small biopsies and cytological specimens: Number 2 in the Series “Pathology for the clinician” Edited by Peter …
The pathological and molecular classification of lung cancer has become substantially more
complex over the past decade. For diagnostic purposes on small samples, additional stains …
complex over the past decade. For diagnostic purposes on small samples, additional stains …
Genomic landscape of atypical adenomatous hyperplasia reveals divergent modes to lung adenocarcinoma
There is a dearth of knowledge about the pathogenesis of premalignant lung lesions,
especially for atypical adenomatous hyperplasia (AAH), the only known precursor for the …
especially for atypical adenomatous hyperplasia (AAH), the only known precursor for the …
Exon 14 deleted MET receptor as a new biomarker and target in cancers
AB Cortot, Z Kherrouche… - Journal of the …, 2017 - academic.oup.com
Inhibitors of the receptor tyrosine kinase (RTK) MET have been ineffective at treating cancer,
possibly because of lack of knowledge that would allow selection of tumors likely to respond …
possibly because of lack of knowledge that would allow selection of tumors likely to respond …
Clinicopathological implications of MET exon 14 mutations in non-small cell lung cancer–A systematic review and meta-analysis
MET exon 14 mutation is an uncommon genomic alteration in non-small cell lung cancer
(NSCLC). This meta-analysis aimed at investigating the clinicopathological and prognostic …
(NSCLC). This meta-analysis aimed at investigating the clinicopathological and prognostic …
New insights into the biology and development of lung cancer in never smokers—implications for early detection and treatment
Lung cancer is the leading cause of cancer deaths worldwide. Despite never smokers
comprising between 10 and 25% of all cases, lung cancer in never smokers (LCNS) is …
comprising between 10 and 25% of all cases, lung cancer in never smokers (LCNS) is …