CRISPR Diagnostics for WHO High-Priority Sexually Transmitted Infections

I Gul, MA Raheem, L Lian, AM Karim, BB Heyat… - TrAC Trends in …, 2024 - Elsevier
Sexually transmitted infections (STIs) pose a global health threat. Most of these infections
are curable if detected in a timely and accurate manner. In 2022, the World Health …

Advancements of CRISPR Technology in Public Health-Related Analysis

X Gu, Q Tang, Y Zhu, C Sun, L Wu, H Ji, Q Wang… - Biosensors and …, 2024 - Elsevier
Pathogens and contaminants in food and the environment present significant challenges to
human health, necessitating highly sensitive and specific diagnostic methods. Traditional …

On-Site Fluorescent Detection of Sepsis-Inducing Bacteria using a Graphene-Oxide CRISPR-Cas12a (GO-CRISPR) System

T Kasputis, Y He, Q Ci, J Chen - Analytical Chemistry, 2024 - ACS Publications
Sepsis is an extremely dangerous medical condition that emanates from the body's
response to a pre-existing infection. Early detection of sepsis-inducing bacterial infections …

Sustainable and efficient strategy for functional Lyocell fiber manufacture through curcumin-loaded nanospheres

Y He, Z Cao, C Deng, L Zheng, J Xu, Z Zhang… - Industrial Crops and …, 2024 - Elsevier
Lyocell fiber is an important choice for functional apparel textiles because of its advantages
of comfort, high strength, sustainable source and pollution-free spinning process. However …

A novel sensitization strategy for uncertain single stranded probe on electrode surface based on terminal deoxynucleotidyl transferase and G-rich spherical nucleic …

H Wang, S Chen, J Liu, W Liu, W Chen, L Huang… - Chemical Engineering …, 2024 - Elsevier
In recent years, RPA-CRISPR/Cas12a-based electrochemical biosensors have emerged as
highly effective tools for nucleic acid detection. However, the random trans-cleavage …

An all-in-one microfluidic SlipChip for power-free and rapid biosensing of pathogenic bacteria

L Xue, M Liao, J Lin - Lab on a Chip, 2024 - pubs.rsc.org
Point-of-care testing of pathogens is becoming more and more important for the prevention
and control of food poisoning. Herein, a power-free colorimetric biosensor was presented for …

CRISPR/Cas9-Mediated Genome Editing of T4 Bacteriophage for High-Throughput Antimicrobial Susceptibility Testing

Y He, J Chen - Analytical Chemistry, 2024 - ACS Publications
The accurate and effective determination of antimicrobial resistance is essential to limiting
the spread of infectious diseases and ensuring human health. Herein, a simple, accurate …

CIMNE-CRISPR: A novel amplification-free diagnostic for rapid early detection of African Swine Fever Virus

T Pal, Z Liu, J Chen - Biosensors and Bioelectronics, 2025 - Elsevier
Abstract African Swine Fever Virus (ASFV) is a highly contagious pathogen with nearly
100% mortality in swine, causing severe global economic loss. Current detection methods …

Novel Anti-CRISPR-Assisted CRISPR Biosensor for Exclusive Detection of Single-Stranded DNA (ssDNA)

Q Ci, Y He, J Chen - ACS sensors, 2024 - ACS Publications
Nucleic acid analysis plays an important role in disease diagnosis and treatment. The
discovery of CRISPR technology has provided novel and versatile approaches to the …

Optical biosensors for the detection of foodborne pathogens: recent development and future prospects

Y Wang, K Jia, J Lin - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Rapid detection of foodborne pathogens is crucial for protecting food safety and minimizing
economic losses. Optical biosensors recognize and quantify pathogenic bacteria through …