The gut microbiota and colorectal surgery outcomes: facts or hype? A narrative review

A Agnes, C Puccioni, D D'Ugo, A Gasbarrini, A Biondi… - BMC surgery, 2021 - Springer
Background The gut microbiota (GM) has been proposed as one of the main determinants of
colorectal surgery complications and theorized as the “missing factor” that could explain still …

[PDF][PDF] Mechanical bowel preparation and antibiotics in elective colorectal surgery: network meta-analysis

J Tan, ÉJ Ryan, MG Davey, FT McHugh, B Creavin… - BJS open, 2023 - academic.oup.com
Background The use of intravenous antibiotics at anaesthetic induction in colorectal surgery
is the standard of care. However, the role of mechanical bowel preparation, enemas, and …

Perioperative oral care can prevent surgical site infection after colorectal cancer surgery: a multicenter, retrospective study of 1,926 cases analyzed by propensity …

H Nobuhara, Y Matsugu, S Soutome, S Hayashida… - Surgery, 2022 - Elsevier
Background Surgical site infection is a common postoperative complication of colorectal
cancer surgery, and surgical site infection increases medical costs, prolongs hospitalization …

Systemic versus Oral and Systemic Antibiotic Prophylaxis (SOAP) study in colorectal surgery: prospective randomized multicentre trial

G Papp, G Saftics, BE Szabó, J Baracs… - British Journal of …, 2021 - academic.oup.com
Background There is no consensus regarding the role of mechanical bowel preparation
(MBP) and oral antibiotic prophylaxis (OABP) in reducing postoperative complications in …

Colon and rectal surgery surgical site infection reduction bundle: to improve is to change

SC Hoang, AA Klipfel, LA Roth, M Vrees… - The American Journal of …, 2019 - Elsevier
Background Despite the introduction of the Surgical Care Improvement Project, surgical site
infections remain a source of morbidity. The aim of this study was to determine the value of …

Comparison of two bundles for reducing surgical site infection in colorectal surgery: multicentre cohort study

M Flores-Yelamos, A Gomila-Grange, JM Badia… - BJS open, 2024 - academic.oup.com
Background There is controversy regarding the maximum number of elements that can be
included in a surgical site infection prevention bundle. In addition, it is unclear whether a …

Prior antibiotics exposure is associated with an elevated risk of surgical site infections, including anastomotic leakage, after colon cancer but not rectal cancer surgery …

SSM Lu, M Rutegård, C Häggström… - … Journal of Cancer, 2024 - Wiley Online Library
Gut microbiota composition has been implicated in surgical site complications after
colorectal cancer surgery. Antibiotics affect gut microbiota, but evidence for a role in surgical …

[HTML][HTML] Incidence of and risk factors for surgical site infection after colorectal surgery: A multiple-center prospective study of 3,663 consecutive patients in China

TY Hou, HQ Gan, JF Zhou, YJ Gong, LY Li… - International Journal of …, 2020 - Elsevier
Background Surgical site infection (SSI) after colorectal surgery (CRS) remains a significant
problem for its negative clinical outcomes. However, it is poorly understood in China. This …

[HTML][HTML] An interventional nationwide surveillance program lowers postoperative infection rates in elective colorectal surgery. A cohort study (2008–2019)

N Arroyo-Garcia, JM Badia, A Vázquez, M Pera… - International Journal of …, 2022 - Elsevier
Background Colorectal surgery is associated with the highest rate of surgical site infection
(SSI). This study analyses the effectiveness of an interventional surveillance program on SSI …

Impact of oral antibiotic prophylaxis on surgical site infection after rectal surgery: results of randomized trial

E Rybakov, M Nagudov, M Sukhina… - International Journal of …, 2021 - Springer
Aim To evaluate the impact of oral antibiotic prophylaxis on surgical site infection (SSI) rate
after rectal surgery. Methods It was a single-center 1: 1 randomized controlled open parallel …