The expression of a foreign protein (s) in a recombinant host cell or organism often utilizes a
significant amount of the host cell's resources, removing those resources away from host cell …

Whereas cell concentrations of 5–10 grams dry cell weight per liter (gDCW/1) are typical of
batch cultures, fed-batch techniques can be used to achieve concentrations greater than 50 …

Experimental elucidation of the metabolic load placed on bacteria by the expression of
foreign protein is presented. The host/vector system is Escherichia coli RR1/pBR329 (ampr …

The temperature inducible expression system, based on the pL and/or pR phage lambda
promoters regulated by the thermolabile cI857 repressor has been widely use to produce …

Chromosomal integration of recombinant genes is desirable compared with expression from
plasmids due to increased stability, reduced cell-to-cell variability, and elimination of the …

Synthesis of recombinant protein (human mini‐proinsulin) is investigated in fed‐batch
cultures at high cell concentration of recombinant Escherichia coli BL21 (DE3)[pET …

Bacillus licheniformis PWD-1, the parent strain, and B. subtilis FDB-29, a recombinant strain.
In both strains, keratinase was induced by proteinaceous media, and repressed by …

Advances in molecular biology and the exploitation of recombinant DNA procedures for the
expression of heterologous genes in microbial hosts offer an opportunity to develop …

The advent of recombinant-DNA (rDNA) technology has provided a direct approach for the
production of a wide range ofbioche~ lfical products from industrial microorganisms, as well …

We use a mathematical model to analyze the dynamics of loss of nonconjugative
pACYC184 from populations of Escherichia coli B in glucose-limited continuous culture. This …