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Natural variation in the binding pocket of a parasitic flatworm TRPM channel resolves the basis for praziquantel sensitivity
The drug praziquantel (PZQ) is the key clinical therapy for treating schistosomiasis and other
infections caused by parasitic flatworms. A schistosome target for PZQ was recently …
infections caused by parasitic flatworms. A schistosome target for PZQ was recently …
Pharmacokinetic variability of anthelmintics: implications for the treatment of neurocysticercosis
H Jung-Cook - Expert Review of Clinical Pharmacology, 2012 - Taylor & Francis
Human neurocysticercosis is a severe disease caused by the installation of Taenia solium
larvae in the CNS. A wide variety of clinical manifestations are related to neurocysticercosis …
larvae in the CNS. A wide variety of clinical manifestations are related to neurocysticercosis …
What about the Cytoskeletal and Related Proteins of Tapeworms in the Host's Immune Response? An Integrative Overview
Recent advances have increased our understanding of the molecular machinery in the
cytoskeleton of mammalian cells, in contrast to the case of tapeworm parasites, where …
cytoskeleton of mammalian cells, in contrast to the case of tapeworm parasites, where …
Cassia alata L: potential role as anthelmintic agent against Hymenolepis diminuta
The efficacy of Cassia alata against cestode Hymenolepis diminuta was evaluated in our
study. Worms were maintained between rat model and beetle. Air-dried leaves of C. alata …
study. Worms were maintained between rat model and beetle. Air-dried leaves of C. alata …
In vitro anthelmintic activities of Khaya anthotheca and Faidherbia albida extracts used in Chad by traditional healers for the treatment of helminthiasis and in silico …
B Christalin, M Besati… - Journal of Tropical …, 2024 - Wiley Online Library
Background. Helminthiasis is endemic in Chad and constitutes a public health problem,
particularly among school‐age children. The aim of this study was to evaluate the …
particularly among school‐age children. The aim of this study was to evaluate the …
Effect of Lysimachia ramosa (Primulaceae) on helminth parasites: motility, mortality and scanning electron microscopic observations on surface topography
M Challam, B Roy, V Tandon - Veterinary Parasitology, 2010 - Elsevier
The alcoholic extract of Lysimachia ramosa Wall (Primulaceae) was tested in vitro against
helminth parasites, Fasciolopsis buski and Ascaris suum, from porcine hosts and Raillietina …
helminth parasites, Fasciolopsis buski and Ascaris suum, from porcine hosts and Raillietina …
The potential for histone deacetylase (HDAC) inhibitors as cestocidal drugs
HR Vaca, AM Celentano, MA Toscanini… - PLoS Neglected …, 2021 - journals.plos.org
Background Echinococcosis and cysticercosis are neglected tropical diseases caused by
cestode parasites (family Taeniidae). Not only there is a small number of approved …
cestode parasites (family Taeniidae). Not only there is a small number of approved …
Chemical composition and broad-spectrum anthelmintic activity of a cultivar of toothache plant, Acmella oleracea, from Mizoram, India
PB Lalthanpuii, K Lalchhandama - Pharmaceutical Biology, 2020 - Taylor & Francis
Context A variety of Acmella oleracea (L.) RK Jansen (Asteraceae) is used by the Mizo
people of India and Myanmar for intestinal helminthiasis. Objective To perform a chemical …
people of India and Myanmar for intestinal helminthiasis. Objective To perform a chemical …
Efficacy of China-made praziquantel for treatment of Schistosomiasis haematobium in Africa: A randomized controlled trial
XY Wang, J He, S Juma, F Kabole, J Guo… - PLoS Neglected …, 2019 - journals.plos.org
Background In the roadmap on the neglected tropical diseases (NTD) the World Health
Organization (WHO) aims at attaining at least 75% coverage of preventive chemotherapy in …
Organization (WHO) aims at attaining at least 75% coverage of preventive chemotherapy in …
A novel pH-sensitive magnetic alginate–chitosan beads for albendazole delivery
FQ Wang, P Li, JP Zhang, AQ Wang… - Drug development and …, 2010 - Taylor & Francis
Background: Drug delivery system using polymer-coated magnetic carriers is considered as
an effective strategy for passive targeting, which can not only increase drug utilization but …
an effective strategy for passive targeting, which can not only increase drug utilization but …