Nanotechnology as a novel approach in combating microbes providing an alternative to antibiotics

B Mubeen, AN Ansar, R Rasool, I Ullah, SS Imam… - Antibiotics, 2021 - mdpi.com
The emergence of infectious diseases promises to be one of the leading mortality factors in
the healthcare sector. Although several drugs are available on the market, newly found …

Pharmacokinetics and pharmacodynamics of antibacterial agents

ME Levison, JH Levison - Infectious disease clinics of North …, 2009 - pmc.ncbi.nlm.nih.gov
The pharmacodynamics of an antimicrobial drug relates its pharmacokinetics to the time
course of the antimicrobial effects at the site of the infection. Knowledge of the drug's …

Fluoroquinolones: mechanism of action, classification, and development of resistance

JM Blondeau - Survey of ophthalmology, 2004 - Elsevier
The fluoroquinolones represent an evolving class of broad-spectrum antimicrobial agents
used in the prevention and treatment of a variety of ocular infections; however, resistance to …

Bacterial keratitis: identifying the areas of clinical uncertainty

S Tuft, TF Somerville, JPO Li, T Neal, S De… - Progress in retinal and …, 2022 - Elsevier
Bacterial keratitis is a common corneal infection that is treated with topical antimicrobials. By
the time of presentation there may already be severe visual loss from corneal ulceration and …

Overview of mechanisms of antibiotic resistance in Pseudomonas aeruginosa: an ocular perspective

D Subedi, AK Vijay, M Willcox - Clinical and Experimental …, 2018 - Taylor & Francis
Treatment of Pseudomonas aeruginosa eye infections often becomes a challenge due to the
ability of this bacterium to be resistant to antibiotics via intrinsic and acquired mechanisms …

Wearable, Biocompatible, and Dual-Emission Ocular Multisensor Patch for Continuous Profiling of Fluoroquinolone Antibiotics in Tears

S Yin, X Chen, R Li, L Sun, C Yao, Z Li - ACS nano, 2024 - ACS Publications
The abuse or misuse of antibiotics in clinical and agricultural settings severely endangers
human health and ecosystems, which has raised profound concerns for public health …

Consensus and controversies in the science of endophthalmitis management: Basic research and clinical perspectives

T Das, J Joseph, MP Simunovic, A Grzybowski… - Progress in retinal and …, 2023 - Elsevier
Infectious endophthalmitis is a severe intraocular infection caused by bacteria, or less
commonly by fungi. It can occur after penetrating eye procedures, trauma, or the spread of …

Practical guidance for clinical microbiology laboratories: diagnosis of ocular infections

SM Leal Jr, KG Rodino, WC Fowler… - Clinical microbiology …, 2021 - journals.asm.org
The variety and complexity of ocular infections have increased significantly in the last
decade since the publication of Cumitech 13B, Laboratory Diagnosis of Ocular Infections …

Pharmaceutical impurities—a mini-review

J Roy - AAPs PharmSciTech, 2002 - Springer
The control of pharmaceutical impurities is currently a critical issue to the pharmaceutical
industry. The International Conference on Harmonization (ICH) has formulated a workable …

[PDF][PDF] Impurity profile: significance in active pharmaceutical ingredient

SB Bari, BR Kadam, YS Jaiswal… - Eurasian J Anal …, 2007 - academia.edu
Various regulatory authorities like ICH, USFDA, Canadian Drug and Health Agency are
emphasizing on the purity requirements and the identification of impurities in Active …