Strategies for enhanced gene delivery to the central nervous system

Z Gao - Nanoscale Advances, 2024 - pubs.rsc.org
The delivery of genes to the central nervous system (CNS) has been a persistent challenge
due to various biological barriers. The blood-brain barrier (BBB), in particular, hampers the …

Sexually dimorphic oxytocin circuits drive intragroup social conflict and aggression in wild house mice

Y Sofer, N Zilkha, E Gimpel, S Wagner… - Nature …, 2024 - nature.com
In nature, both males and females engage in competitive aggressive interactions to resolve
social conflicts, yet the behavioral principles guiding such interactions and their underlying …

Sex diversity in the 21st century: concepts, frameworks, and approaches for the future of neuroendocrinology

KO Smiley, KM Munley, K Aghi, SE Lipshutz… - Hormones and …, 2024 - Elsevier
Sex is ubiquitous and variable throughout the animal kingdom. Historically, scientists have
used reductionist methodologies that rely on a priori sex categorizations, in which two …

Leveraging the unique social organization of California mice to study circuit-specific effects of oxytocin on behavior

AA Lake, BC Trainor - Hormones and behavior, 2024 - Elsevier
Oxytocin is a versatile neuropeptide that modulates many different forms of social behavior.
Recent hypotheses pose that oxytocin enhances the salience of rewarding and aversive …

Oxytocin facilitates social behavior of female rats via selective modulation of interneurons in the medial prefrontal cortex

S Schimmer, A Lefevre, J Lebedeva, A Rozov, A Kania… - bioRxiv, 2024 - biorxiv.org
The hypothalamic neuropeptide oxytocin is best known for its prosocial behavioral effects.
However, the precise anatomical and cellular targets for oxytocin in the cortex during social …

Advancements in the study of neural mechanisms underlying mammalian grou** behaviour

AM Kelly - Frontiers in Ethology, 2023 - frontiersin.org
Despite the prevalence of large group-living in the animal kingdom, we know surprisingly
little about how the brain facilitates grou** behavior, particularly in mammals. In this brief …