Immunomodulation by radiotherapy in tumour control and normal tissue toxicity

UM Cytlak, DP Dyer, J Honeychurch… - Nature Reviews …, 2022 - nature.com
Radiotherapy (RT) is a highly effective anticancer treatment that is delivered to more than
half of all patients with cancer. In addition to the well-documented direct cytotoxic effects, RT …

Mechanisms of apoptosis modulation by curcumin: Implications for cancer therapy

K Mortezaee, E Salehi… - Journal of cellular …, 2019 - Wiley Online Library
Cancer incidences are growing and cause millions of deaths worldwide. Cancer therapy is
one of the most important challenges in medicine. Improving therapeutic outcomes from …

Curcumin as an anti‐inflammatory agent: Implications to radiotherapy and chemotherapy

B Farhood, K Mortezaee, NH Goradel… - Journal of cellular …, 2019 - Wiley Online Library
Cancer is the second cause of death worldwide. Chemotherapy and radiotherapy are the
most common modalities for the treatment of cancer. Experimental studies have shown that …

Nanoplastics as a potential environmental health factor: effects of polystyrene nanoparticles on human intestinal epithelial Caco-2 cells

C Cortés, J Domenech, M Salazar, S Pastor… - Environmental …, 2020 - pubs.rsc.org
The ubiquitous and increasing presence of micro-/nanoplastics (MNPLs) in our environment
demands an urgent hazard assessment, in order to determine the potential risk they pose to …

Radiation-induced skin reactions: mechanism and treatment

J Wei, L Meng, X Hou, C Qu, B Wang… - Cancer management …, 2018 - Taylor & Francis
Radiotherapy (RT) is a major treatment for malignant tumors. The latest data show that>
70% of patients with malignant tumors need RT at different periods. Skin changes can be …

[HTML][HTML] Ionizing radiation-induced circulatory and metabolic diseases

S Tapio, MP Little, JC Kaiser, N Impens… - Environment …, 2021 - Elsevier
Risks to health are the prime consideration in all human situations of ionizing radiation
exposure and therefore of relevance to radiation protection in all occupational, medical, and …

Radiation‐induced normal tissue damage: oxidative stress and epigenetic mechanisms

J Wei, B Wang, H Wang, L Meng… - Oxidative medicine …, 2019 - Wiley Online Library
Radiotherapy (RT) is currently one of the leading treatments for various cancers; however, it
may cause damage to healthy tissue, with both short‐term and long‐term side effects …

[HTML][HTML] Comprehensive toxicity risk profiling in radiation therapy for head and neck cancer: A new concept for individually optimised treatment

L Van den Bosch, A van der Schaaf… - Radiotherapy and …, 2021 - Elsevier
Background and purpose A comprehensive individual toxicity risk profile is needed to
improve radiation treatment optimisation, minimising toxicity burden, in head and neck …

Melatonin as an adjuvant in radiotherapy for radioprotection and radiosensitization

B Farhood, NH Goradel, K Mortezaee… - Clinical and …, 2019 - Springer
It is estimated that more than half of cancer patients undergo radiotherapy during the course
of their treatment. Despite its beneficial therapeutic effects on tumor cells, exposure to high …

Nuclear and radiological emergencies: biological effects, countermeasures and biodosimetry

E Obrador, R Salvador-Palmer, JI Villaescusa… - Antioxidants, 2022 - mdpi.com
Atomic and radiological crises can be caused by accidents, military activities, terrorist
assaults involving atomic installations, the explosion of nuclear devices, or the utilization of …