On the nature and use of models in network neuroscience
Network theory provides an intuitively appealing framework for studying relationships
among interconnected brain mechanisms and their relevance to behaviour. As the space of …
among interconnected brain mechanisms and their relevance to behaviour. As the space of …
Genetic dissection of neural circuits: a decade of progress
Tremendous progress has been made since Neuron published our Primer on genetic
dissection of neural circuits 10 years ago. Since then, cell-type-specific anatomical …
dissection of neural circuits 10 years ago. Since then, cell-type-specific anatomical …
Survey of spiking in the mouse visual system reveals functional hierarchy
The anatomy of the mammalian visual system, from the retina to the neocortex, is organized
hierarchically. However, direct observation of cellular-level functional interactions across this …
hierarchically. However, direct observation of cellular-level functional interactions across this …
Dissociable dopamine dynamics for learning and motivation
The dopamine projection from ventral tegmental area (VTA) to nucleus accumbens (NAc) is
critical for motivation to work for rewards and reward-driven learning. How dopamine …
critical for motivation to work for rewards and reward-driven learning. How dopamine …
[HTML][HTML] Multi-sensory gamma stimulation ameliorates Alzheimer's-associated pathology and improves cognition
We previously reported that inducing gamma oscillations with a non-invasive light flicker
(gamma entrainment using sensory stimulus or GENUS) impacted pathology in the visual …
(gamma entrainment using sensory stimulus or GENUS) impacted pathology in the visual …
Breathing coordinates cortico-hippocampal dynamics in mice during offline states
Network dynamics have been proposed as a mechanistic substrate for the information
transfer across cortical and hippocampal circuits. However, little is known about the …
transfer across cortical and hippocampal circuits. However, little is known about the …
Ultraflexible electrode arrays for months-long high-density electrophysiological map** of thousands of neurons in rodents
Penetrating flexible electrode arrays can simultaneously record thousands of individual
neurons in the brains of live animals. However, it has been challenging to spatially map and …
neurons in the brains of live animals. However, it has been challenging to spatially map and …
Solving the spike sorting problem with Kilosort
Spike sorting is the computational process of extracting the firing times of single neurons
from recordings of local electrical fields. This is an important but hard problem in …
from recordings of local electrical fields. This is an important but hard problem in …
Spatiotemporal dynamics of noradrenaline during learned behaviour
Noradrenaline released from the locus coeruleus (LC) is a ubiquitous neuromodulator,,–that
has been linked to multiple functions including arousal,,–, action and sensory gain,–, and …
has been linked to multiple functions including arousal,,–, action and sensory gain,–, and …
Spike sorting with Kilosort4
Spike sorting is the computational process of extracting the firing times of single neurons
from recordings of local electrical fields. This is an important but hard problem in …
from recordings of local electrical fields. This is an important but hard problem in …