Nesfatin-1: A biomarker and potential therapeutic target in neurological disorders
S Zhou, J Nao - Neurochemical Research, 2024 - Springer
Nesfatin-1 is a novel adipocytokine consisting of 82 amino acids with anorexic and anti-
hyperglycemic properties. Further studies of nesfatin-1 have shown it to be closely …
hyperglycemic properties. Further studies of nesfatin-1 have shown it to be closely …
Bursts of brain erosion: seizures and age-dependent neurological vulnerability
Hypersynchronous and exaggerated neuronal firing, exemplified by epileptiform activity and
seizures, are disruptors of brain function across acute and chronic neuropathological …
seizures, are disruptors of brain function across acute and chronic neuropathological …
Valproic acid attenuated PTZ-induced oxidative stress, inflammation, and apoptosis in the SH-SY5Y cells via modulating the TRPM2 channel
Valproic acid (VPA) is one of the most widely used antiepileptic drugs. The protective role of
VPA and the role of the TRPM2 channel in this mechanism in develo** neuronal damage …
VPA and the role of the TRPM2 channel in this mechanism in develo** neuronal damage …
SARS-CoV-2 Causes Brain Damage: Therapeutic Intervention with AZD8797
Elevated CX3CL1 is associated with severe COVID-19 and neurologic symptoms. We aimed
to investigate the potential protective effects of selective CX3CR1 antagonist AZD8797 on …
to investigate the potential protective effects of selective CX3CR1 antagonist AZD8797 on …
Glucagon-like peptide-1 receptor in the human hypothalamus is associated with body mass index and colocalizes with the anorexigenic neuropeptide nucleobindin-2 …
Data on animals emphasize the importance of the neuronal glucagon-like peptide-1 (GLP-1)
receptor (GLP-1R) for feeding suppression, although it is unclear whether astrocytes …
receptor (GLP-1R) for feeding suppression, although it is unclear whether astrocytes …
Nesfatin-1 suppresses autophagy of chondrocytes in osteoarthritis via remodeling of cytoskeleton and inhibiting RhoA/ROCK signal pathway
L Jiang, SAA Moqbel, J Zhu, Q Fu, J Lai, C Lin… - Journal of Orthopaedic …, 2023 - Springer
Autophagy and cytoskeleton integrity of chondrocytes are a considered as major factors in
the progression of osteoarthritis (OA) involving excessive chondrocyte apoptosis and …
the progression of osteoarthritis (OA) involving excessive chondrocyte apoptosis and …
Intracerebroventricular administration of the exercise hormone irisin or acute strenuous exercise alleviates epileptic seizure-induced neuroinflammation and improves …
ZN Ozdemir-Kumral, T Akgün, C Haşim, E Ulusoy… - BMC neuroscience, 2024 - Springer
Background Status epilepticus is a common and potentially life-threatening neurological
emergency with a high risk for cognitive and neurobiological impairment. Our aim was to …
emergency with a high risk for cognitive and neurobiological impairment. Our aim was to …
Nesfatin-1 exerts anticonvulsant effect by reducing oxidative stress in experimental epilepsy model
Neuropeptides play an important role in the pathogenesis of epilepsy. In the present study,
the effect of nesfatin-1, a neuropeptide, was investigated on penicillin-induced epilepsy …
the effect of nesfatin-1, a neuropeptide, was investigated on penicillin-induced epilepsy …
[PDF][PDF] Peripheral nesfatin-1 reduces basal brain activity but has limited effect on epilepsy-like conditions.
In this study, we investigated the effects of peripheral nesfatin-1 on basal brain activity and 4-
aminopyridine (4-AP)-induced epileptiform activity, and its relationship with the …
aminopyridine (4-AP)-induced epileptiform activity, and its relationship with the …
Nesfatin-1 Exerts a Neuroprotective Effect in Thioacetamide-Induced Acute Hepatic Encephalopathy by Activating the PI3K/Akt/Nrf2 Pathway
H Faheem, R Alawadhi, H Khattab, RA Abd Ellatif… - 2024 - researchsquare.com
Nesfatin-1 possesses antioxidative and antiapoptotic properties. It can protect against
subarachnoid hemorrhage and brain-induced injury by reducing the activation of the pro …
subarachnoid hemorrhage and brain-induced injury by reducing the activation of the pro …