Raman spectroscopy for chemical biology research

K Dodo, K Fujita, M Sodeoka - Journal of the American Chemical …, 2022 - ACS Publications
In chemical biology research, various fluorescent probes have been developed and used to
visualize target proteins or molecules in living cells and tissues, yet there are limitations to …

[HTML][HTML] Recent advancements in single-cell metabolic analysis for pharmacological research

Y Hou, H Yao, JM Lin - Journal of Pharmaceutical Analysis, 2023 - Elsevier
Cellular heterogeneity is crucial for understanding tissue biology and disease
pathophysiology. Pharmacological research is being advanced by single-cell metabolic …

Noise learning of instruments for high-contrast, high-resolution and fast hyperspectral microscopy and nanoscopy

H He, M Cao, Y Gao, P Zheng, S Yan, JH Zhong… - Nature …, 2024 - nature.com
The low scattering efficiency of Raman scattering makes it challenging to simultaneously
achieve good signal-to-noise ratio (SNR), high imaging speed, and adequate spatial and …

P-ring: the conserved nature of phosphorus enriched cells in seedling roots of distantly related species

A Acharya, TC Pesacreta - Plant Signaling & Behavior, 2023 - Taylor & Francis
Plants require sunlight, carbon dioxide, water and mineral ions for their growth and
development. Roots in vascular plants sequester water and ions from soil and transport …

[HTML][HTML] Microscopic water dispersion and hydrogen-bonding structures in margarine spreads with Raman hyperspectral imaging and machine learning

JN Taylor, K Bando, S Tsukagoshi, L Tanaka, K Fujita… - Food Chemistry, 2025 - Elsevier
Margarine, a water-in-oil (W/O) emulsion, offers advantages such as lower costs in
comparison to similar products, but large amounts of saturated fats pose health risks …

Strategies and progress of Raman technologies for cellular uptake analysis of the drug delivery systems

Y Liu, M Li, H Liu, C Kang, X Yu - International Journal of …, 2023 - Taylor & Francis
Nanoparticle (NP)-based drug delivery systems have the potential to significantly enhance
the pharmacological and therapeutic properties of drugs. These systems enhance the …

Label-free evaluation of maturation and hepatotoxicity of human iPSC-derived hepatocytes using hyperspectral Raman imaging

M Li, Y Ueyama-Toba, M Lindley, G Kongklad… - Analytical …, 2023 - ACS Publications
To promote the clinical application of human induced pluripotent stem cell (hiPSC)-derived
hepatocytes, a method capable of monitoring regenerative processes and assessing …

Lipid droplets as cell fate determinants in skeletal muscle

J Chen, JF Markworth, C Ferreira, C Zhang… - Trends in Endocrinology …, 2024 - cell.com
Lipid droplets (LDs) are dynamic organelles that communicate with other cellular
components to orchestrate energetic homeostasis and signal transduction. In skeletal …

Electrode-and Label-Free Assessment of Electrophysiological Firing Rates through Cytochrome C Monitoring via Raman Spectroscopy

C Tentellino, M d'Amora, R Melikov, G Iachetta… - ACS …, 2025 - ACS Publications
In vitro neurotoxicology aims to assess and predict the side effects of exogenous chemicals
toward the human brain. Among the exploited approaches, electrophysiological techniques …

[HTML][HTML] Spontaneous Raman bioimaging–Looking to 2050

AJ Hobro, NI Smith - Vibrational Spectroscopy, 2024 - Elsevier
Raman imaging has been employed for a wide range of biological sample analyses, is often
chosen for its non-invasiveness, and ability to provide rich information from samples with …