G protein–coupled receptors (GPCRs) play critical roles in regulating processes such as
cellular homeostasis, responses to stimuli, and cell signaling. Accordingly, GPCRs have …

Malignant ovarian tumors bear the highest mortality rate among all gynecological cancers.
Both late tumor diagnosis and tolerance to available chemical therapy increase patient …

Ovarian cancer (OC) causes significant morbidity and mortality as neither detection nor
screening of OC is currently feasible at an early stage. Difficulty to promptly diagnose OC in …

Ovarian cancer is a frequent malignancy that affects a large percentage of women.
Endometriosis is a chronic condition, where there is a production of benign lesions were …

Programmed cell death ligand 1 (PD-L1) is an immune checkpoint protein frequently
expressed in human cancers that contributes to immune evasion through its binding to PD-1 …

The lack of symptoms at the early stages of clear cell renal cell carcinoma (ccRCC) allows
the tumour to metastasize, leading to a dramatic reduction in patient survival. Therefore, we …

Epigenetic modifications such as histone modification play an important role in
tumorigenesis. There are several evidence that histone deacetylases (HDACs) play a key …

G protein-coupled receptors (GPCRs) play a key role in regulating the homeostasis of the
internal environment and are closely associated with tumour progression as major …

Simple Summary The large amount of knowledge regarding epigenetic pathways has
opened a broad range of treatments that provide hope for adult patients with highly …

As negative modulators of G-protein-coupled receptors (GPCRs) signaling, regulators of G
protein signaling (RGS) proteins facilitate various downstream cellular signalings through …