Host defense peptide mimicking antimicrobial amino acid polymers and beyond: Design, synthesis and biomedical applications

Y Wu, K Chen, J Wang, M Chen, Y Chen, Y She… - Progress in Polymer …, 2023 - Elsevier
Microbial infections endanger human health and life. Conventional antibiotics has saved
countless human lives, however, is seriously challenged by the quick emergence of …

Epsilon-poly-L-lysine: recent advances in biomanufacturing and applications

L Wang, C Zhang, J Zhang, Z Rao, X Xu… - … in Bioengineering and …, 2021 - frontiersin.org
ε-poly-L-lysine (ε-PL) is a naturally occurring poly (amino acid) of varying polymerization
degree, which possesses excellent antimicrobial activity and has been widely used in food …

A Biomimetic Mussel‐Inspired ε‐Poly‐l‐lysine Hydrogel with Robust Tissue‐Anchor and Anti‐Infection Capacity

R Wang, J Li, W Chen, T Xu, S Yun, Z Xu… - Advanced Functional …, 2017 - Wiley Online Library
In situ hydrogels have attracted considerable attention in tissue engineering because of their
minimal invasiveness and ability to match the irregular tissue defects. However, hydrous …

[HTML][HTML] Efficiency of multifunctional antibacterial hydrogels for chronic wound healing in diabetes: a comprehensive review

JY Ji, DY Ren, YZ Weng - International journal of nanomedicine, 2022 - ncbi.nlm.nih.gov
Diabetic chronic wounds or amputation, which are complications of diabetes mellitus (DM),
are a cause of great suffering for diabetics. In addition to the lack of oxygen, elevated …

Microbial Metabolite Inspired β‐Peptide Polymers Displaying Potent and Selective Antifungal Activity

D Zhang, C Shi, Z Cong, Q Chen, Y Bi… - Advanced …, 2022 - Wiley Online Library
Potent and selective antifungal agents are urgently needed due to the quick increase of
serious invasive fungal infections and the limited antifungal drugs available. Microbial …

Co-production of levan with other high-value bioproducts: A review

EC de Siqueira, ET Öner - International Journal of Biological …, 2023 - Elsevier
Levan is a homopolysaccharide of fructose that has both scientific and industrial importance,
with various applications in health, pharmaceutical, cosmetic and food industries. Despite its …

Engineering Streptomyces albulus to enhance ε-poly-L-lysine production by introducing a polyphosphate kinase-mediated ATP regeneration system

H Yang, D Zhu, L Kai, L Wang, H Zhang, J Zhang… - Microbial Cell …, 2023 - Springer
Background ε-Poly-L-lysine (ε-PL) is a natural and safe food preservative that is mainly
produced by filamentous and aerobic bacteria Streptomyces albulus. During ε-PL …

Development of next-generation antimicrobial hydrogel dressing to combat burn wound infection

Z Kopecki - Bioscience Reports, 2021 - portlandpress.com
Infection of burn wounds often leads to poor healing, sepsis, disability, or even death.
Traditional care focuses on early debridement, fluid resuscitation, and intravenous …

Organocatalyzed ring-opening polymerization of cyclic lysine derivative: sustainable access to cationic poly (ε-lysine) mimics

J Chen, Y Dong, C **ao, Y Tao, X Wang - Macromolecules, 2021 - ACS Publications
Poly (ε-lysine) has broad applications and is dominantly produced via fermentation. Our
group successfully realized the chemosynthesis of poly (ε-lysine) through ring-opening …

Biotechnological production and application of epsilon-poly-L-lysine (ε-PL): biosynthesis and its metabolic regulation

D Wang, H Wang, J Wu, Y Hou, J Sun, J Yuan… - World Journal of …, 2022 - Springer
Abstract Epsilon-poly-L-lysine (ε-PL) is an unusual biopolymer composed of L-lysine
produced by several microorganisms, especially by the genus Streptomyces. Due to its …