[HTML][HTML] Diabetes mellitus—Progress and opportunities in the evolving epidemic
Diabetes, a complex multisystem metabolic disorder characterized by hyperglycemia, leads
to complications that reduce quality of life and increase mortality. Diabetes pathophysiology …
to complications that reduce quality of life and increase mortality. Diabetes pathophysiology …
Feeding gut microbes to nourish the brain: unravelling the diet–microbiota–gut–brain axis
The prevalence of brain disorders, including stress-related neuropsychiatric disorders and
conditions with cognitive dysfunction, is rising. Poor dietary habits contribute substantially to …
conditions with cognitive dysfunction, is rising. Poor dietary habits contribute substantially to …
On the pathogenesis of obesity: Causal models and missing pieces of the puzzle
Application of the physical laws of energy and mass conservation at the whole-body level is
not necessarily informative about causal mechanisms of weight gain and the development of …
not necessarily informative about causal mechanisms of weight gain and the development of …
The gut-brain axis mediates bacterial driven modulation of reward signaling
Objective Our goal is to investigate if microbiota composition modulates reward signaling
and assess the role of the vagus in mediating microbiota to brain communication. Methods …
and assess the role of the vagus in mediating microbiota to brain communication. Methods …
Dietary polyphenols regulate appetite mechanism via gut-brain axis and gut homeostasis
Nowadays, due to the rise of fast-food consumption, the metabolic diseases are increasing
as a result of high-sugar and high-fat diets. Therefore, there is an urgent need for natural …
as a result of high-sugar and high-fat diets. Therefore, there is an urgent need for natural …
[HTML][HTML] The vagus nerve: An old but new player in brain–body communication
L Ma, HB Wang, K Hashimoto - Brain, Behavior, and Immunity, 2024 - Elsevier
The vagus nerve is a crucial component of the parasympathetic nervous system, facilitating
communication between the brain and various organs including the ears, heart, lungs …
communication between the brain and various organs including the ears, heart, lungs …
AgRP neuron activity promotes associations between sensory and nutritive signals to guide flavor preference
NT Nyema, AD McKnight, AG Vargas-Elvira… - Molecular …, 2023 - Elsevier
Objective The learned associations between sensory cues (eg, taste, smell) and nutritive
value (eg, calories, post-ingestive signaling) of foods powerfully influences our eating …
value (eg, calories, post-ingestive signaling) of foods powerfully influences our eating …
[HTML][HTML] Sucrose overconsumption impairs AgRP neuron dynamics and promotes palatable food intake
CM Lorch, NW Hayes, JL **a, SW Fleps, HE McMorrow… - Cell reports, 2024 - cell.com
Rapid gut-brain communication is critical to maintain energy balance and is disrupted in diet-
induced obesity. In particular, the role of carbohydrate overconsumption in the regulation of …
induced obesity. In particular, the role of carbohydrate overconsumption in the regulation of …
Hepatic vagal afferents convey clock-dependent signals to regulate circadian food intake
Circadian desynchrony induced by shiftwork or jet lag is detrimental to metabolic health, but
how synchronous or desynchronous signals are transmitted among tissues is unknown. We …
how synchronous or desynchronous signals are transmitted among tissues is unknown. We …
[HTML][HTML] Molecular Pharmacology of Vitamin C and Relevance to Health and Obesity—A Narrative Review
The role of food constituents as pharmacological agents is an important consideration in
health and obesity. Vitamin C acts as a small molecule antioxidant but is also a co-factor for …
health and obesity. Vitamin C acts as a small molecule antioxidant but is also a co-factor for …