Background: Patients with CKD frequently have anemia that results from iron-restricted
erythropoiesis and inflammation. Anemia of CKD is currently managed with iron …

Anemia is a major health condition associated with chronic kidney disease (CKD). A key
underlying cause of this disorder is iron deficiency. Although intravenous iron treatment can …

Rodent and cell‐culture models support a role for iron‐related adipokine dysregulation and
insulin resistance in the pathogenesis of nonalcoholic fatty liver disease (NAFLD); however …

Hepcidin is a peptide hormone which helps in regulating iron homeostasis in the human
body. Iron obtained from daily diet is passed through the intestinal enterocyte apical …

Iron is an essential element for all living organisms, but produces toxic oxidants. Thus, iron
homeostasis is tightly regulated in mammals. Hepcidin-25 (hepcidin) has emerged as a …

Background Both anaemia and red blood cell (RBC) transfusion are common and
associated with adverse outcomes in patients admitted to the intensive care unit (ICU). The …

Background Chronic kidney disease (CKD) is a significant risk factor for cardiovascular
disease (CVD) and death. Increased oxidative stress in people with CKD has been …

Introduction: It was suggested that pentoxifylline (PTX) might improve the response to
recombinant human erythropoietin (rhEPO) in anemic hemodialysis (HD) patients. However …

Aims Lower haemoglobin levels are common among females without kidney diseases.
However, little is known about the sex‐specific management of anaemia in haemodialysis …

Background Hemodialysis (HD) patients often have elevated levels of hepcidin hormone,
which is a key regulator of systemic iron homeostasis. While pentoxifylline (PTX) has been …