Cells release small, phospholipid membrane-enclosed particles, collectively referred to as
extracellular vesicles (EVs), into their surroundings to enable intercellular communication …

A transcriptome constructed from short-read RNA sequencing (RNA-seq) is an easily
attainable proxy catalog of protein-coding genes when genome assembly is unnecessary …

RNA sequencing (RNA-seq) is one of the most widely used technologies in transcriptomics
as it can reveal the relationship between the genetic alteration and complex biological …

Nanotechnology has enabled the development of innovative therapeutics, diagnostics, and
drug delivery systems. Nanoparticles (NPs) can influence gene expression, protein …

Motivation As one of important epigenetic modifications, DNA N4-methylcytosine (4mC) is
recently shown to play crucial roles in restriction–modification systems. For better …

To gain a better understanding of the complexity of gene expression in normal and diseased
tissues it is important to account for the spatial context and identity of cells in situ. State-of …

Photoperiods integrate with the circadian clock to coordinate gene expression rhythms and
thus ensure plant fitness to the environment. Genome-wide characterization and comparison …

Abstract Analysis of differential gene expression from RNA-seq data has become a standard
for several research areas. The steps for the computational analysis include many data …

Background Alzheimer's disease (AD) is a neurodegenerative disorder and the predominant
type of dementia worldwide. It is characterized by the progressive and irreversible decline of …

Abstract Urinary Extracellular Vesicles (uEV) have emerged as a source for biomarkers of
kidney damage, holding potential to replace the conventional invasive techniques including …