This review covers current knowledge of selenium in the dietary intake, its bioavailability,
metabolism, functions, biomarkers, supplementation and toxicity, as well as its relationship …

Selenium (Se) is a potent nutritional antioxidant that carries out biological effects through its
incorporation into selenoproteins. Given the crucial roles that selenoproteins play in …

Hayes' Principles and Methods of Toxicology has long been established as a reliable and
informative reference for the concepts, methodologies, and assessments integral to …

Glutathione peroxidase and thioredoxin reductase are major selenoenzymes through which
selenium exerts powerful antioxidant effects. Selenium also elicits pro-oxidant effects at toxic …

Selenium (Se) is an essential dietary component for animals including humans and is
regarded as a protective agent against cancer. Although the mode of anticancer action of Se …

Selenium (Se) is a dietary essential trace element with important biological roles.
Accumulating evidence indicates that Se compounds possess anticancer properties. Se is …

With our growing understanding of the pathways involved in cell proliferation and signaling,
targeted therapies, in the treatment of cancer are entering the clinical arena. New and …

Cancer is the most common cause of death worldwide. Annually, more than ten million new
cancer cases are diagnosed, and more than six million deaths occur due to cancer …

Although the average daily dietary selenium (Se) intake in the United States is consistently
above the adult RDA of 55μg Se/day, supranutritional supplements of 200μg Se/day have …

Selenium (Se) is an essential dietary trace element participating in the regulation of various
physiological functions in humans, farm animals and poultry through its incorporation into a …