Psoriatic arthritis: pathogenesis and targeted therapies

AB Azuaga, J Ramírez, JD Cañete - International journal of molecular …, 2023 - mdpi.com
Psoriatic arthritis (PsA), a heterogeneous chronic inflammatory immune-mediated disease
characterized by musculoskeletal inflammation (arthritis, enthesitis, spondylitis, and …

Sex-and gender-related differences in psoriatic arthritis

S Tarannum, YY Leung, SR Johnson… - Nature Reviews …, 2022 - nature.com
Psoriatic arthritis (PsA) is an inflammatory musculoskeletal disease with a chronic,
progressive course. Various aspects of PsA, including its clinical features, disease course …

Comorbidities in psoriatic arthritis: a systematic review and meta-analysis

S Gupta, Z Syrimi, DM Hughes, SS Zhao - Rheumatology international, 2021 - Springer
The aims of this systematic review and meta-analysis were to:(1) describe the prevalence of
commonly reported comorbidities in psoriatic arthritis (PsA),(2) compare the incidence …

Applying precision medicine to unmet clinical needs in psoriatic disease

DR Jadon, C Stober, SR Pennington… - Nature Reviews …, 2020 - nature.com
Psoriatic disease (PsD) is a heterogeneous condition that can affect peripheral and axial
joints (arthritis), entheses, skin (psoriasis) and other structures. Over the past decade …

Determinants of patient‐reported psoriatic arthritis impact of disease: an analysis of the association with sex in 458 patients from fourteen countries

AM Orbai, J Perin, C Gorlier, LC Coates… - Arthritis care & …, 2020 - Wiley Online Library
Objective Sex differences may modify symptoms, disease expression, and treatment effects.
The objective of this study was to evaluate the link between life impact and sex in psoriatic …

Impact of comorbidities on patient-reported outcomes in psoriatic arthritis: a single centre cohort study

G Biedroń, M Wilk, J Nowakowski, P Kuszmiersz… - Rheumatology …, 2024 - Springer
Background Comorbidities are frequent in psoriatic arthritis (PsA) and may contribute to
worse health-related outcomes. Patient-reported outcomes (PROs) are used to evaluate the …

Sex differences in the efficacy, safety and persistence of patients with psoriatic arthritis treated with tofacitinib: a post-hoc analysis of phase 3 trials and long-term …

L Eder, DD Gladman, P Mease, RA Pollock, R Luna… - RMD open, 2023 - rmdopen.bmj.com
Background Evaluate the impact of sex on tofacitinib efficacy, safety and persistence (time to
discontinuation) in patients with psoriatic arthritis (PsA). Methods Data were pooled from two …

Treatment persistence of biologics among patients with psoriatic arthritis

A Haddad, T Gazitt, I Feldhamer, J Feld… - Arthritis Research & …, 2021 - Springer
Background Persistence of biologic therapy in psoriatic arthritis (PsA) patients is an
important factor in individualized patient treatment planning and healthcare policy and …

Sex-related differences in patient characteristics, and efficacy and safety of advanced therapies in randomised clinical trials in psoriatic arthritis: a systematic literature …

L Eder, S Mylvaganam, JP Pardo, J Petkovic… - The Lancet …, 2023 - thelancet.com
Background Sex-related differences in clinical manifestations and disease outcomes exist in
psoriatic arthritis, however, there is limited information on sex-related differences in …

Real‐world six‐and twelve‐month drug retention, remission, and response rates of secukinumab in 2,017 patients with psoriatic arthritis in thirteen European countries

B Michelsen, S Georgiadis, D Di Giuseppe… - Arthritis care & …, 2022 - Wiley Online Library
Objective There is a lack of real‐life studies on interleukin‐17 (IL‐17) inhibition in psoriatic
arthritis (PsA). We assessed real‐life 6‐and 12‐month effectiveness (ie, retention, remission …