Advances in the therapeutic delivery and applications of functionalized Pluronics: A critical review

P Singla, S Garg, J McClements, O Jamieson… - Advances in colloid and …, 2022 - Elsevier
Abstract Pluronic (PEO-PPO-PEO) block copolymers can form nano-sized micelles with a
structure composed of a hydrophobic PPO core and hydrophilic PEO shell layer. Pluronics …

Nanomedicine strategies for heating “cold” ovarian cancer (OC): next evolution in immunotherapy of OC

Y Yang, T Zhao, Q Chen, Y Li, Z **ao… - Advanced …, 2022 - Wiley Online Library
Immunotherapy has revolutionized cancer treatment, dramatically improving survival rates of
melanoma and lung cancer patients. Nevertheless, immunotherapy is almost ineffective …

Progress in natural compounds/siRNA co-delivery employing nanovehicles for cancer therapy

M Ashrafizadeh, A Zarrabi, K Hushmandi… - ACS combinatorial …, 2020 - ACS Publications
Chemotherapy using natural compounds, such as resveratrol, curcumin, paclitaxel,
docetaxel, etoposide, doxorubicin, and camptothecin, is of importance in cancer therapy …

[HTML][HTML] Self-assembled nanoformulations of paclitaxel for enhanced cancer theranostics

Q Pei, B Jiang, D Hao, Z **e - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Chemotherapy has occupied the critical position in cancer therapy, especially towards the
post-operative, advanced, recurrent, and metastatic tumors. Paclitaxel (PTX)-based …

Engineered exosomes as drug and RNA co-delivery system: new hope for enhanced therapeutics?

H Chen, H Yao, J Chi, C Li, Y Liu, J Yang… - … in Bioengineering and …, 2023 - frontiersin.org
Chemotherapy often faces some obstacles such as low targeting effects and drug
resistance, which introduce the low therapeutic efficiency and strong side effects. Recent …

Circular RNA ITCH: A novel tumor suppressor in multiple cancers

Y Li, Y Ge, L Xu, R Jia - Life sciences, 2020 - Elsevier
Circular RNAs (circRNAs) are a new type of endogenous noncoding RNAs with closed
circular structure. Emerging evidence indicates that circRNAs play crucial roles in many …

[HTML][HTML] Targeted drug conjugate systems for ovarian cancer chemotherapy

OD Ogundipe, O Olajubutu, SK Adesina - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Ovarian cancer is a highly lethal disease that affects women. Early diagnosis and treatment
of women with early-stage disease improve the probability of survival. Unfortunately, the …

Co-delivery of paclitaxel (PTX) and docosahexaenoic acid (DHA) by targeting lipid nanoemulsions for cancer therapy

B Li, T Tan, W Chu, Y Zhang, Y Ye, S Wang, Y Qin… - Drug Delivery, 2022 - Taylor & Francis
Breast cancer is one of the most common types of cancer in female patients with high
morbidity and mortality. Multi-drug chemotherapy has significant advantages in the treatment …

An overview of saturated cyclic ethers: Biological profiles and synthetic strategies

Q Lu, DS Harmalkar, Y Choi, K Lee - Molecules, 2019 - mdpi.com
Saturated oxygen heterocycles are widely found in a broad array of natural products and
other biologically active molecules. In medicinal chemistry, small and medium rings are also …

Photo-triggered self-destructive ROS-responsive nanoparticles of high paclitaxel/chlorin e6 co-loading capacity for synergetic chemo-photodynamic therapy

X Yang, X Shi, Y Zhang, J Xu, J Ji, L Ye, F Yi… - Journal of Controlled …, 2020 - Elsevier
To improve the anti-cancer therapeutic effect of nanosystems for chemo-photodynamic
therapy, there remain several hurdles to be addressed, eg, limited co-loading efficiency …