The X chromosome and male infertility
The X chromosome is a key player in germ cell development, as has been highlighted for
males in previous studies revealing that the mammalian X chromosome is enriched in genes …
males in previous studies revealing that the mammalian X chromosome is enriched in genes …
Y chromosome functions in mammalian spermatogenesis
J Subrini, J Turner - Elife, 2021 - elifesciences.org
The mammalian Y chromosome is critical for male sex determination and spermatogenesis.
However, linking each Y gene to specific aspects of male reproduction has been …
However, linking each Y gene to specific aspects of male reproduction has been …
Recombination-aware phylogenomics reveals the structured genomic landscape of hybridizing cat species
Current phylogenomic approaches implicitly assume that the predominant phylogenetic
signal within a genome reflects the true evolutionary history of organisms, without assessing …
signal within a genome reflects the true evolutionary history of organisms, without assessing …
Fourth report on chicken genes and chromosomes 2022
The chicken continues to hold its position as a leading model organism within many areas of
research, as well as being a major source of protein for human consumption. The First …
research, as well as being a major source of protein for human consumption. The First …
Molecular evolution across mouse spermatogenesis
Genes involved in spermatogenesis tend to evolve rapidly, but we lack a clear
understanding of how protein sequences and patterns of gene expression evolve across this …
understanding of how protein sequences and patterns of gene expression evolve across this …
A neofunctionalized X-linked ampliconic gene family is essential for male fertility and equal sex ratio in mice
AN Kruger, MA Brogley, JL Huizinga, JM Kidd… - Current Biology, 2019 - cell.com
The mammalian sex chromosomes harbor an abundance of newly acquired ampliconic
genes, although their functions require elucidation [1–9]. Here, we demonstrate that the X …
genes, although their functions require elucidation [1–9]. Here, we demonstrate that the X …
Massive gene amplification on a recently formed Drosophila Y chromosome
Widespread loss of genes on the Y is considered a hallmark of sex chromosome
differentiation. Here we show that the initial stages of Y evolution are driven by massive …
differentiation. Here we show that the initial stages of Y evolution are driven by massive …
Unraveling patterns of disrupted gene expression across a complex tissue
Whole tissue RNASeq is the standard approach for studying gene expression divergence in
evolutionary biology and provides a snapshot of the comprehensive transcriptome for a …
evolutionary biology and provides a snapshot of the comprehensive transcriptome for a …
Genetic conflict and the origin of multigene families: implications for sex chromosome evolution
Sex chromosomes are havens for intragenomic conflicts. The absence of recombination
between sex chromosomes creates the opportunity for the evolution of segregation …
between sex chromosomes creates the opportunity for the evolution of segregation …
Differential sperm motility mediates the sex ratio drive sha** mouse sex chromosome evolution
The mouse sex chromosomes exhibit an extraordinary level of copy number amplification of
postmeiotically expressed genes [1, 2], driven by an" arms race"(genomic conflict) between …
postmeiotically expressed genes [1, 2], driven by an" arms race"(genomic conflict) between …