Technology of deep brain stimulation: current status and future directions

JK Krauss, N Lipsman, T Aziz, A Boutet… - Nature Reviews …, 2021 - nature.com
Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …

Deep brain stimulation in movement disorders: from experimental surgery to evidence‐based therapy

P Krack, J Volkmann, G Tinkhauser… - Movement …, 2019 - Wiley Online Library
Deep brain stimulation (DBS) of 3 different targets is the most important therapeutic
innovation of the past 30 years for patients with fluctuating Parkinson's disease (PD) …

[HTML][HTML] Lead-DBS v3. 0: Map** deep brain stimulation effects to local anatomy and global networks

C Neudorfer, K Butenko, S Oxenford, N Rajamani… - Neuroimage, 2023 - Elsevier
Following its introduction in 2014 and with support of a broad international community, the
open-source toolbox Lead-DBS has evolved into a comprehensive neuroimaging platform …

Bootstrap** random forest and CHAID for prediction of white spot disease among shrimp farmers

MO Edeh, S Dalal, IC Obagbuwa, BVVS Prasad… - Scientific Reports, 2022 - nature.com
Technology is playing an important role is healthcare particularly as it relates to disease
prevention and detection. This is evident in the COVID-19 era as different technologies were …

Probabilistic sweet spots predict motor outcome for deep brain stimulation in Parkinson disease

TA Dembek, J Roediger, A Horn, P Reker… - Annals of …, 2019 - Wiley Online Library
Objective To investigate whether functional sweet spots of deep brain stimulation (DBS) in
the subthalamic nucleus (STN) can predict motor improvement in Parkinson disease (PD) …

Optimal deep brain stimulation sites and networks for cervical vs. generalized dystonia

A Horn, MM Reich, S Ewert, N Li, B Al-Fatly… - Proceedings of the …, 2022 - pnas.org
Dystonia is a debilitating disease with few treatment options. One effective option is deep
brain stimulation (DBS) to the internal pallidum. While cervical and generalized forms of …

Network localization of cervical dystonia based on causal brain lesions

DT Corp, J Joutsa, RR Darby, CCS Delnooz… - Brain, 2019 - academic.oup.com
Cervical dystonia is a neurological disorder characterized by sustained, involuntary
movements of the head and neck. Most cases of cervical dystonia are idiopathic, with no …

Towards adaptive deep brain stimulation: clinical and technical notes on a novel commercial device for chronic brain sensing

Y Thenaisie, C Palmisano, A Canessa… - Journal of neural …, 2021 - iopscience.iop.org
Objective. Technical advances in deep brain stimulation (DBS) are crucial to improve
therapeutic efficacy and battery life. We report the potentialities and pitfalls of one of the first …

Non-motor outcomes depend on location of neurostimulation in Parkinson's disease

JN Petry-Schmelzer, M Krause, TA Dembek, A Horn… - Brain, 2019 - academic.oup.com
Deep brain stimulation of the subthalamic nucleus is an effective and established therapy for
patients with advanced Parkinson's disease improving quality of life, motor symptoms and …

Probabilistic map** of deep brain stimulation: insights from 15 years of therapy

GJB Elias, A Boutet, SE Joel, J Germann… - Annals of …, 2021 - Wiley Online Library
Deep brain stimulation (DBS) depends on precise delivery of electrical current to target
tissues. However, the specific brain structures responsible for best outcome are still debated …