Epilepsy is one of the most common and disabling neurologic conditions, yet we have an
incomplete understanding of the detailed pathophysiology and, thus, treatment rationale for …

Objectives To compare the time to treatment failure, remission and first seizure of 12 AEDs
(carbamazepine, phenytoin, sodium valproate, phenobarbitone, oxcarbazepine, lamotrigine …

The use of essential oils (EOs) and their components is known since long in traditional
medicine and aromatherapy for the management of various diseases, and is further …

Antiepileptic drugs (AEDs) have many benefits but also many side effects, including
aggression, agitation, and irritability, in some patients with epilepsy. This article offers a …

Electroencephalography is mandatory to determine the epilepsy syndrome. However, for the
precise localization of the irritative zone in patients with focal epilepsy, costly and sometimes …

Consciousness is essential to normal human life. In epileptic seizures consciousness is
often transiently lost, which makes it impossible for the individual to experience or respond …

Adenosine acts in parallel as a neuromodulator and as a homeostatic modulator in the
central nervous system. Its neuromodulatory role relies on a balanced activation of inhibitory …

Diverse brain insults, including traumatic brain injury, stroke, infections, tumors,
neurodegenerative diseases, and prolonged acute symptomatic seizures, such as complex …

Purpose: To provide 1995 estimates of the lifetime and annual cost of epilepsy in the United
States using data from patients with epilepsy, and adjusting for the effects of comorbidities …

Fundamental work on the mechanisms leading to focal epileptic discharges in mesial
temporal lobe epilepsy (MTLE) often rests on the use of rodent models in which an initial …