Primary open-angle glaucoma
Primary Open-Angle Glaucoma | New England Journal of Medicine Skip to main content The
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
Consensus recommendations for trabecular meshwork cell isolation, characterization and culture
Cultured trabecular meshwork (TM) cells are a valuable model system to study the cellular
mechanisms involved in the regulation of conventional outflow resistance and thus …
mechanisms involved in the regulation of conventional outflow resistance and thus …
Gene therapy and gene correction: targets, progress, and challenges for treating human diseases
MR Cring, VC Sheffield - Gene therapy, 2022 - nature.com
The field of gene therapy has made significant strides over the last several decades toward
the treatment of previously untreatable genetic disease. Gene therapy techniques have …
the treatment of previously untreatable genetic disease. Gene therapy techniques have …
CRISPR-Cas9–based treatment of myocilin-associated glaucoma
Primary open-angle glaucoma (POAG) is a leading cause of irreversible vision loss
worldwide, with elevated intraocular pressure (IOP) a major risk factor. Myocilin (MYOC) …
worldwide, with elevated intraocular pressure (IOP) a major risk factor. Myocilin (MYOC) …
Major review: Molecular genetics of primary open-angle glaucoma
Glaucoma is a leading cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), the most common type, is a complex inherited disorder that is …
glaucoma (POAG), the most common type, is a complex inherited disorder that is …
Roles of exosomes in the normal and diseased eye
Exosomes are nanometer-sized vesicles that are released by cells in a controlled fashion
and mediate a plethora of extra-and intercellular activities. Some key functions of exosomes …
and mediate a plethora of extra-and intercellular activities. Some key functions of exosomes …
Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma
Mutations in myocilin (MYOC) are the most common genetic cause of primary open angle
glaucoma (POAG), but the mechanisms underlying MYOC-associated glaucoma are not fully …
glaucoma (POAG), but the mechanisms underlying MYOC-associated glaucoma are not fully …
Primary open-angle glaucoma genes
JH Fingert - Eye, 2011 - nature.com
A substantial fraction of glaucoma has a genetic basis. About 5% of primary open angle
glaucoma (POAG) is currently attributed to single-gene or Mendelian forms of glaucoma (ie …
glaucoma (POAG) is currently attributed to single-gene or Mendelian forms of glaucoma (ie …
Glaucomatous outflow pathway and oxidative stress
Oxidative free radicals and reactive oxygen species (ROS) are able to affect the cellularity of
the human trabecular meshwork (HTM). These findings suggest that intraocular pressure …
the human trabecular meshwork (HTM). These findings suggest that intraocular pressure …
The genetics of primary open-angle glaucoma: a review
Glaucoma is the major cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), as the most prevalent form of glaucoma, is a complex inherited disorder …
glaucoma (POAG), as the most prevalent form of glaucoma, is a complex inherited disorder …