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[HTML][HTML] Metallo-drugs in cancer therapy: Past, present and future
Cancer treatments which include conventional chemotherapy have not proven very
successful in curing human malignancies. The failures of these treatment modalities include …
successful in curing human malignancies. The failures of these treatment modalities include …
[HTML][HTML] NAMI-A and KP1019/1339, two iconic ruthenium anticancer drug candidates face-to-face: A case story in medicinal inorganic chemistry
NAMI-A ((ImH)[trans-RuCl4 (dmso-S)(Im)], Im= imidazole) and KP1019/1339
(KP1019=(IndH)[trans-RuCl4 (Ind) 2], Ind= indazole; KP1339= Na [trans-RuCl4 (Ind) 2]) are …
(KP1019=(IndH)[trans-RuCl4 (Ind) 2], Ind= indazole; KP1339= Na [trans-RuCl4 (Ind) 2]) are …
[HTML][HTML] Bioactivity and development of small non-platinum metal-based chemotherapeutics
Countless expectations converge in the multidisciplinary endeavour for the search and
development of effective and safe drugs in fighting cancer. Although they still embody a …
development of effective and safe drugs in fighting cancer. Although they still embody a …
Metallodrugs: an approach against invasion and metastasis in cancer treatment
MM González‐Ballesteros, C Mejía… - FEBS Open …, 2022 - Wiley Online Library
Cancer is a heterogeneous and multifactorial disease that causes high mortality throughout
the world; therefore, finding the most effective therapies is a major research challenge …
the world; therefore, finding the most effective therapies is a major research challenge …
Recent advances and application of ruthenium complexes in tumor malignancy
R Kanaoujiya, S Srivastava, R Singh… - Materials Today …, 2023 - Elsevier
Ruthenium-based complexes have a wide range of targets and mechanisms for anticancer
activities. For the treatment of malignant malignancy, ruthenium-based drugs have special …
activities. For the treatment of malignant malignancy, ruthenium-based drugs have special …
Recent considerations in the application of RAPTA‐C for cancer treatment and perspectives for its combination with immunotherapies
M Rausch, PJ Dyson… - Advanced …, 2019 - Wiley Online Library
The organometallic ruthenium (II)[Ru (arene) Cl2PTA] PTA‐1, 3, 5‐triaza‐7‐
phosphaadamantane compound, RAPTA‐C, represents an innovative anti‐cancer …
phosphaadamantane compound, RAPTA‐C, represents an innovative anti‐cancer …
The Lipid Metabolism as Target and Modulator of BOLD‐100 Anticancer Activity: Crosstalk with Histone Acetylation
D Baier, T Mendrina, B Schoenhacker‐Alte… - Advanced …, 2023 - Wiley Online Library
The leading first‐in‐class ruthenium‐complex BOLD‐100 currently undergoes clinical phase‐
II anticancer evaluation. Recently, BOLD‐100 is identified as anti‐Warburg compound. The …
II anticancer evaluation. Recently, BOLD‐100 is identified as anti‐Warburg compound. The …
Towards anticancer fluoroquinolones: A review article
Different studies about the anticancer potential of several medically used antibacterial
fluoroquinolones have been established. Fluoroquinolone derivatives, like some anti …
fluoroquinolones have been established. Fluoroquinolone derivatives, like some anti …
Exploring cellular uptake, accumulation and mechanism of action of a cationic Ru-based nanosystem in human preclinical models of breast cancer
According to WHO, breast cancer incidence is increasing so that the search for novel
chemotherapeutic options is nowadays an essential requirement to fight neoplasm …
chemotherapeutic options is nowadays an essential requirement to fight neoplasm …
The anticancer activity of indazole compounds: a mini review
C Shang, Y Hou, T Meng, M Shi… - Current Topics in …, 2021 - benthamdirect.com
The incidence and mortality of cancer continue to grow since the current medical treatments
often fail to produce a complete and durable tumor response and ultimately give rise to …
often fail to produce a complete and durable tumor response and ultimately give rise to …