[HTML][HTML] Metallo-drugs in cancer therapy: Past, present and future

RL Lucaciu, AC Hangan, B Sevastre, LS Oprean - Molecules, 2022 - mdpi.com
Cancer treatments which include conventional chemotherapy have not proven very
successful in curing human malignancies. The failures of these treatment modalities include …

[HTML][HTML] Bioactivity and development of small non-platinum metal-based chemotherapeutics

MG Ferraro, M Piccolo, G Misso, R Santamaria, C Irace - Pharmaceutics, 2022 - mdpi.com
Countless expectations converge in the multidisciplinary endeavour for the search and
development of effective and safe drugs in fighting cancer. Although they still embody a …

Metallodrugs: an approach against invasion and metastasis in cancer treatment

MM González‐Ballesteros, C Mejía… - FEBS Open …, 2022 - Wiley Online Library
Cancer is a heterogeneous and multifactorial disease that causes high mortality throughout
the world; therefore, finding the most effective therapies is a major research challenge …

Recent advances and application of ruthenium complexes in tumor malignancy

R Kanaoujiya, S Srivastava, R Singh… - Materials Today …, 2023 - Elsevier
Ruthenium-based complexes have a wide range of targets and mechanisms for anticancer
activities. For the treatment of malignant malignancy, ruthenium-based drugs have special …

Recent considerations in the application of RAPTA‐C for cancer treatment and perspectives for its combination with immunotherapies

M Rausch, PJ Dyson… - Advanced …, 2019 - Wiley Online Library
The organometallic ruthenium (II)[Ru (arene) Cl2PTA] PTA‐1, 3, 5‐triaza‐7‐
phosphaadamantane compound, RAPTA‐C, represents an innovative anti‐cancer …

The Lipid Metabolism as Target and Modulator of BOLD‐100 Anticancer Activity: Crosstalk with Histone Acetylation

D Baier, T Mendrina, B Schoenhacker‐Alte… - Advanced …, 2023 - Wiley Online Library
The leading first‐in‐class ruthenium‐complex BOLD‐100 currently undergoes clinical phase‐
II anticancer evaluation. Recently, BOLD‐100 is identified as anti‐Warburg compound. The …

Towards anticancer fluoroquinolones: A review article

MAA Abdel‐Aal, SA Abdel‐Aziz… - Archiv Der …, 2019 - Wiley Online Library
Different studies about the anticancer potential of several medically used antibacterial
fluoroquinolones have been established. Fluoroquinolone derivatives, like some anti …

The anticancer activity of indazole compounds: a mini review

C Shang, Y Hou, T Meng, M Shi… - Current Topics in …, 2021 - benthamdirect.com
The incidence and mortality of cancer continue to grow since the current medical treatments
often fail to produce a complete and durable tumor response and ultimately give rise to …