Immunobiology and pathogenesis of hepatitis B virus infection
Hepatitis B virus (HBV) is a non-cytopathic, hepatotropic virus with the potential to cause a
persistent infection, ultimately leading to cirrhosis and hepatocellular carcinoma. Over the …
persistent infection, ultimately leading to cirrhosis and hepatocellular carcinoma. Over the …
A roadmap for serum biomarkers for hepatitis B virus: current status and future outlook
A Kramvis, KM Chang, M Dandri, P Farci… - Nature Reviews …, 2022 - nature.com
Globally, 296 million people are infected with hepatitis B virus (HBV), and approximately one
million people die annually from HBV-related causes, including liver cancer. Although there …
million people die annually from HBV-related causes, including liver cancer. Although there …
Cancer‐associated fibroblast‐mediated cellular crosstalk supports hepatocellular carcinoma progression
M Song, J He, QZ Pan, J Yang, J Zhao, YJ Zhang… - …, 2021 - Wiley Online Library
Background and Aims Cancer‐associated fibroblasts (CAFs) are key players in multicellular,
stromal‐dependent alterations leading to HCC pathogenesis. However, the intricate …
stromal‐dependent alterations leading to HCC pathogenesis. However, the intricate …
Modeling SARS-CoV-2 and HBV co-dynamics with optimal control
Clinical reports have shown that chronic hepatitis B virus (HBV) patients co-infected with
SARS-CoV-2 have a higher risk of complications with liver disease than patients without …
SARS-CoV-2 have a higher risk of complications with liver disease than patients without …
The scientific basis of combination therapy for chronic hepatitis B functional cure
Functional cure of chronic hepatitis B (CHB)—or hepatitis B surface antigen (HBsAg) loss
after 24 weeks off therapy—is now the goal of treatment, but is rarely achieved with current …
after 24 weeks off therapy—is now the goal of treatment, but is rarely achieved with current …
Progress towards elimination goals for viral hepatitis
The global burden of viral hepatitis is substantial; in terms of mortality, hepatitis B virus and
hepatitis C virus infections are on a par with HIV, malaria and tuberculosis, among the top …
hepatitis C virus infections are on a par with HIV, malaria and tuberculosis, among the top …
Hepatitis B virus persistence and reactivation
Y Shi, M Zheng - bmj, 2020 - bmj.com
Hepatitis B virus (HBV) infection causes chronic hepatitis and has long term complications.
Individuals ever infected with HBV are at risk of viral reactivation under certain …
Individuals ever infected with HBV are at risk of viral reactivation under certain …
Xalnesiran with or without an Immunomodulator in Chronic Hepatitis B
J Hou, W Zhang, Q **e, R Hua, H Tang… - … England Journal of …, 2024 - Mass Medical Soc
Background Xalnesiran, a small interfering RNA molecule that targets a conserved region of
the hepatitis B virus (HBV) genome and silences multiple HBV transcripts, may have …
the hepatitis B virus (HBV) genome and silences multiple HBV transcripts, may have …
[HTML][HTML] Viral hepatitis: Past, present, and future
Each hepatitis virus—Hepatitis A, B, C, D, E, and G—poses a distinct scenario to the patient
and clinician alike. Since the discovery of each virus, extensive knowledge regarding …
and clinician alike. Since the discovery of each virus, extensive knowledge regarding …
Medicinal chemistry strategies for discovering antivirals effective against drug-resistant viruses
Y Ma, E Frutos-Beltrán, D Kang… - Chemical Society …, 2021 - pubs.rsc.org
During the last forty years we have witnessed impressive advances in the field of antiviral
drug discovery culminating with the introduction of therapies able to stop human …
drug discovery culminating with the introduction of therapies able to stop human …