Sensing creatinine in urine via the iontronic response of enzymatic single solid-state nanochannels

LMH Parra, G Laucirica, ME Toimil-Molares… - Biosensors and …, 2025 - Elsevier
In this study, we investigate the integration of the enzyme creatinine deiminase into solid-
state nanopore walls through electrostatic assembly for the development of creatinine …

Thrombin Nanochannel Logic Gate Inspired by BioMemory

Y Chen, X Yue, Y Tang, Q Zhu, W Yu, M Luo… - Analytical …, 2024 - ACS Publications
The process of “reading” and “writing” in biomemory involves the transmission of electrical
signals between neurons, with ligand-gated ion channels assuming a key role. The solid …

Dynamic Response of Ionic Current in Conical Nanopores

Z Liu, L Ma, H Zhang, J Zhuang, J Man… - … Applied Materials & …, 2024 - ACS Publications
Ionic current rectification (ICR) of charged conical nanopores has various applications in
fields including nanofluidics, biosensing, and energy conversion, whose function is closely …

Harnessing concerted functions in confined environments: cascading enzymatic reactions in nanofluidic biosensors for sensitive detection of arginine

ME Gramajo, LO Maffoni, LMH Parra… - Chemical …, 2025 - pubs.rsc.org
We developed an arginine-responsive biosensor by integrating cascade enzymatic
reactions into nanochannels functionalized with weak polyelectrolytes, which serve as …