Pancreatic cancer in 2021: What you need to know to win

V Tonini, M Zanni - World Journal of Gastroenterology, 2021 - pmc.ncbi.nlm.nih.gov
Pancreatic cancer is one of the solid tumors with the worst prognosis. Five-year survival rate
is less than 10%. Surgical resection is the only potentially curative treatment, but the tumor is …

Targeted therapy for pancreatic ductal adenocarcinoma: Mechanisms and clinical study

HC Kung, J Yu - MedComm, 2023 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and lethal malignancy with a
high rate of recurrence and a dismal 5‐year survival rate. Contributing to the poor prognosis …

3d tissue models as tools for radiotherapy screening for pancreatic cancer

G Wishart, P Gupta, G Schettino… - The British Journal of …, 2021 - academic.oup.com
The efficiency of radiotherapy treatment regimes varies from tumour to tumour and from
patient to patient but it is generally highly influenced by the tumour microenvironment (TME) …

[HTML][HTML] Prognostic and predictive value of CA 19-9 in locally advanced pancreatic cancer treated with multiagent induction chemotherapy: results from a prospective …

I Hartlapp, D Valta-Seufzer, JT Siveke, H Algül… - ESMO open, 2022 - Elsevier
Background The prognostic and predictive value of carbohydrate antigen 19-9 (CA 19-9) in
locally advanced pancreatic cancer (LAPC) has not yet been defined from prospective …

In neoadjuvant FOLFIRINOX chemotherapy for pancreatic ductal adenocarcinoma, which response is the more reliable indicator for prognosis, radiologic or …

WG Yun, Y Han, YJ Cho, HS Jung, M Lee… - Annals of Surgical …, 2024 - Springer
Background In this era of increasing neoadjuvant chemotherapy, methods for evaluating
responses to neoadjuvant chemotherapy are still diverse among institutions. Additionally …

[HTML][HTML] Gemcitabine/nab-paclitaxel versus FOLFIRINOX in locally advanced pancreatic cancer: A European multicenter study

N Williet, A Petrillo, G Roth, M Ghidini, M Petrova… - Cancers, 2021 - mdpi.com
Simple Summary Gemcitabine/nab-paclitaxel (GN) and FOLFIRINOX (FFX) are two standard
first-line therapies for metastatic pancreatic cancer (PC) but have rarely been compared …

Neoadjuvant therapy in pancreatic cancer: A review and update on recent trials

W Lo, A Zureikat - Current Opinion in Gastroenterology, 2022 - journals.lww.com
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Prognosticators for patients with pancreatic ductal adenocarcinoma who received neoadjuvant FOLFIRINOX or Gemcitabine/Nab-Paclitaxel therapy and …

YT Tong, Z Lai, MHG Katz, LR Prakash, H Wang… - Cancers, 2023 - mdpi.com
Simple Summary This study is to examine the clinical and pathologic characteristics and
survival in patients who received neoadjuvant FOLFINOX or neoadjuvant gemcitabine/nab …

Towards an updated view on the clinical management of pancreatic adenocarcinoma: Current and future perspectives

L Pekarek, O Fraile-Martinez… - Oncology …, 2021 - spandidos-publications.com
Pancreatic cancer has a dire prognosis and will represent the second leading cause of
cancer death in the next 10 years. The multifactorial approach represents one of the main …

Current treatment of potentially resectable pancreatic ductal adenocarcinoma: a medical oncologist's perspective

VHF de Jesus, RP Riechelmann - Cancer Control, 2023 - journals.sagepub.com
Pancreatic cancer has traditionally been associated with a dismal prognosis, even in early
stages of the disease. In recent years, the introduction of newer generation chemotherapy …