[HTML][HTML] The role of lipid metabolism in COVID-19 virus infection and as a drug target

M Abu-Farha, TA Thanaraj, MG Qaddoumi… - International journal of …, 2020 - mdpi.com
The current Coronavirus disease 2019 or COVID-19 pandemic has infected over two million
people and resulted in the death of over one hundred thousand people at the time of writing …

Influenza A virus cell entry, replication, virion assembly and movement

D Dou, R Revol, H Östbye, H Wang… - Frontiers in …, 2018 - frontiersin.org
Influenza viruses replicate within the nucleus of the host cell. This uncommon RNA virus trait
provides influenza with the advantage of access to the nuclear machinery during replication …

[HTML][HTML] Characterization of the lipidomic profile of human coronavirus-infected cells: implications for lipid metabolism remodeling upon coronavirus replication

B Yan, H Chu, D Yang, KH Sze, PM Lai, S Yuan… - Viruses, 2019 - mdpi.com
Lipids play numerous indispensable cellular functions and are involved in multiple steps in
the replication cycle of viruses. Infections by human-pathogenic coronaviruses result in …

Lipid rafts in immune signalling: current progress and future perspective

P Varshney, V Yadav, N Saini - Immunology, 2016 - Wiley Online Library
Lipid rafts are dynamic assemblies of proteins and lipids that harbour many receptors and
regulatory molecules and so act as a platform for signal transduction. They float freely within …

[HTML][HTML] Influenza virus assembly and budding

JS Rossman, RA Lamb - Virology, 2011 - Elsevier
Influenza A virus causes seasonal epidemics, sporadic pandemics and is a significant
global health burden. Influenza virus is an enveloped virus that contains a segmented …

Model systems, lipid rafts, and cell membranes

K Simons, WLC Vaz - Annu. Rev. Biophys. Biomol. Struct., 2004 - annualreviews.org
▪ Abstract Views of how cell membranes are organized are presently changing. The lipid
bilayer that constitutes these membranes is no longer understood to be a homogeneous …

Cholesterol, lipid rafts, and disease

K Simons, R Ehehalt - The Journal of clinical investigation, 2002 - jci.org
Nonstandard abbreviations used: glycophosphatidylinositolanchored (GPI-anchored);
endothelial nitric oxide synthase (eNOS); β-secretase (BACE); endoplasmic reticulum (ER); …

The influenza a virus replication cycle: a comprehensive review

T Carter, M Iqbal - Viruses, 2024 - mdpi.com
Influenza A virus (IAV) is the primary causative agent of influenza, colloquially called the flu.
Each year, it infects up to a billion people, resulting in hundreds of thousands of human …

The state of lipid rafts: from model membranes to cells

M Edidin - Annual review of biophysics and biomolecular …, 2003 - annualreviews.org
▪ Abstract Lipid raft microdomains were conceived as part of a mechanism for the
intracellular trafficking of lipids and lipid-anchored proteins. The raft hypothesis is based on …

Influenza A: understanding the viral life cycle

T Samji - The Yale journal of biology and medicine, 2009 - pmc.ncbi.nlm.nih.gov
Influenza A virus belongs to the family of Orthomyxoviridae. It is an enveloped virus with a
negative sense RNA segmented genome that encodes for 11 viral genes. This virus has …