Lactoferrin: A glycoprotein that plays an active role in human health

X Cao, Y Ren, Q Lu, K Wang, Y Wu, YH Wang… - Frontiers in …, 2023 - frontiersin.org
Lactoferrin (Lf), existing widely in human and mammalian milk, is a multifunctional
glycoprotein with many functions, such as immune regulation, anti-inflammation …

Transition metals and virulence in bacteria

LD Palmer, EP Skaar - Annual review of genetics, 2016 - annualreviews.org
Transition metals are required trace elements for all forms of life. Due to their unique
inorganic and redox properties, transition metals serve as cofactors for enzymes and other …

Molecular de-extinction of ancient antimicrobial peptides enabled by machine learning

JRMA Maasch, MDT Torres, MCR Melo… - Cell Host & Microbe, 2023 - cell.com
Molecular de-extinction could offer avenues for drug discovery by reintroducing bioactive
molecules that are no longer encoded by extant organisms. To prospect for antimicrobial …

Lactoferrin in a context of inflammation-induced pathology

ML Kruzel, M Zimecki, JK Actor - Frontiers in immunology, 2017 - frontiersin.org
Much progress has been achieved to elucidate the function of lactoferrin (LTF), an iron-
binding glycoprotein, in the milieu of immune functionality. This review represents a unique …

Mechanisms of host adaptation by bacterial pathogens

MF Barber, JR Fitzgerald - FEMS microbiology reviews, 2024 - academic.oup.com
The emergence of new infectious diseases poses a major threat to humans, animals, and
broader ecosystems. Defining factors that govern the ability of pathogens to adapt to new …

Molecular evolution of transition metal bioavailability at the host–pathogen interface

GT Antelo, AJ Vila, DP Giedroc, DA Capdevila - Trends in microbiology, 2021 - cell.com
The molecular evolution of the adaptive response at the host–pathogen interface has been
frequently referred to as an'arms race'between the host and bacterial pathogens. The innate …

Laponite/lactoferrin hydrogel loaded with eugenol for methicillin-resistant Staphylococcus aureus-infected chronic skin wound healing

R Zhou, W Zhang, Y Zhang, X Wu, J Huang, R Bo… - Journal of Tissue …, 2024 - Elsevier
Severe bacterial infections can give rise to protracted wound healing processes, thereby
posing a significant risk to a patient's well-being. Consequently, the development of a …

Lactoferrin: a critical mediator of both host immune response and antimicrobial activity in response to streptococcal infections

J Lu, J Francis, RS Doster, KP Haley… - ACS infectious …, 2020 - ACS Publications
Streptococcal species are Gram-positive bacteria responsible for a variety of disease
outcomes including pneumonia, meningitis, endocarditis, erysipelas, necrotizing fasciitis …

The preparation of lactoferrin/magnesium silicate lithium injectable hydrogel and application in promoting wound healing

B Wang, J Zhao, W Lu, Y Ma, X Wang, X An… - International Journal of …, 2022 - Elsevier
The development of novel wound dressings with highly effective antibacterial and
accelerating wound healing properties has become the focus of current research. In this …

[HTML][HTML] Functions of saliva

N Maddu - Saliva and salivary diagnostics, 2019 - intechopen.com
Saliva is produced and secreted by salivary glands. The basic secretary units of salivary
glands are clusters of acini cells. It is fluid that contains water, electrolytes, mucus, and …