Self‐healing polymeric hydrogel formed by metal–ligand coordination assembly: design, fabrication, and biomedical applications

L Shi, P Ding, Y Wang, Y Zhang… - Macromolecular …, 2019 - Wiley Online Library
Self‐healing hydrogels based on metal–ligand coordination chemistry provide new and
exciting properties that improve injectability, rheological behaviors, and even biological …

The relationship between the chemistry and biological activity of the bisphosphonates

FH Ebetino, AML Hogan, S Sun, MK Tsoumpra, X Duan… - Bone, 2011 - Elsevier
The ability of bisphosphonates ((HO) 2 P (O) CR 1 R 2 P (O)(OH) 2) to inhibit bone
resorption has been known since the 1960s, but it is only recently that a detailed molecular …

Bisphosphonate-Anchored PEGylation and Radiolabeling of Superparamagnetic Iron Oxide: Long-Circulating Nanoparticles for in Vivo Multimodal (T1 MRI-SPECT) …

L Sandiford, A Phinikaridou, A Protti, LK Meszaros… - Acs Nano, 2013 - ACS Publications
The efficient delivery of nanomaterials to specific targets for in vivo biomedical imaging is
hindered by rapid sequestration by the reticuloendothelial system (RES) and consequent …

Targeted delivery to bone and mineral deposits using bisphosphonate ligands

LE Cole, T Vargo-Gogola, RK Roeder - Advanced drug delivery reviews, 2016 - Elsevier
The high concentration of mineral present in bone and pathological calcifications is unique
compared with all other tissues and thus provides opportunity for targeted delivery of …

A nuclear chocolate box: the periodic table of nuclear medicine

PJ Blower - Dalton Transactions, 2015 - pubs.rsc.org
Radioisotopes of elements from all parts of the periodic table find both clinical and research
applications in radionuclide molecular imaging and therapy (nuclear medicine). This article …

NF-κB as a therapeutic target in inflammatory-associated bone diseases

TH Lin, J Pajarinen, L Lu, A Nabeshima… - Advances in protein …, 2017 - Elsevier
Inflammation is a defensive mechanism for pathogen clearance and maintaining tissue
homeostasis. In the skeletal system, inflammation is closely associated with many bone …

99mTc-Bisphosphonate-Iron Oxide Nanoparticle Conjugates for Dual-Modality Biomedical Imaging

R Torres Martin de Rosales, R Tavaré… - Bioconjugate …, 2011 - ACS Publications
The combination of radionuclide-based imaging modalities such as single photon emission
computed tomography (SPECT) and positron emission tomography (PET) with magnetic …

Metallic radionuclides in the development of diagnostic and therapeutic radiopharmaceuticals

S Bhattacharyya, M Dixit - Dalton transactions, 2011 - pubs.rsc.org
Metallic radionuclides are the mainstay of both diagnostic and therapeutic
radiopharmaceuticals. Therapeutic nuclear medicine is less advanced but has tremendous …

Radiolabeled iron oxide nanoparticles as dual modality contrast agents in SPECT/MRI and PET/MRI

MA Karageorgou, P Bouziotis, E Stiliaris… - Nanomaterials, 2023 - mdpi.com
During the last decades, the utilization of imaging modalities such as single photon emission
computed tomography (SPECT), positron emission tomography (PET), and magnetic …

Fucoidan prolongs the circulation time of dextran-coated iron oxide nanoparticles

MRA Abdollah, TJ Carter, C Jones, TL Kalber… - ACS …, 2018 - ACS Publications
The magnetic properties and safety of dextran-coated superparamagnetic iron oxide
nanoparticles (SPIONs) have facilitated their clinical use as MRI contrast agents and …