[HTML][HTML] Mouse gastrulation: Coordination of tissue patterning, specification and diversification of cell fate

ES Bardot, AK Hadjantonakis - Mechanisms of development, 2020 - Elsevier
During mouse embryonic development a mass of pluripotent epiblast tissue is transformed
during gastrulation to generate the three definitive germ layers: endoderm, mesoderm, and …

Development in a Dish—In Vitro Models of Mammalian Embryonic Development

Y El Azhar, KF Sonnen - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Despite decades of research, the complex processes of embryonic development are not fully
understood. The study of mammalian development poses particular challenges such as low …

Lightsheet microscopy

L Dyer, A Parker, K Paphiti, J Sanderson - Current Protocols, 2022 - Wiley Online Library
In this paper, we review lightsheet (selective plane illumination) microscopy for mouse
developmental biologists. There are different means of forming the illumination sheet, and …

A uterus‐inspired niche drives blastocyst development to the early organogenesis

Z Gu, J Guo, J Zhai, G Feng, X Wang, Z Gao… - Advanced …, 2022 - Wiley Online Library
The fundamental physical features such as the mechanical properties and microstructures of
the uterus need to be considered when building in vitro culture platforms to mimic the uterus …

Revealing molecular and cellular heterogeneity in hypopharyngeal carcinogenesis through single-cell RNA and TCR/BCR sequencing

CW Tie, JQ Zhu, Z Yu, LZ Dou, ML Wang… - Frontiers in …, 2024 - frontiersin.org
Introduction Hypopharyngeal squamous cell carcinoma (HSCC) is one of the malignant
tumors with the worst prognosis in head and neck cancers. The transformation from normal …

Watching the embryo: Evolution of the microscope for the study of embryogenesis

S Iyer, S Mukherjee, M Kumar - BioEssays, 2021 - Wiley Online Library
Embryos and microscopes share a long, remarkable history and biologists have always
been intrigued to watch how embryos develop under the microscope. Here we discuss the …

Visualizing Mouse Embryo Gastrulation Epithelial-Mesenchymal Transition Through Single Cell Labeling Followed by Ex Vivo Whole Embryo Live Imaging

W Nahaboo, B Saykali, N Mathiah… - The Epithelial-to …, 2021 - Springer
Epithelial-mesenchymal transition (EMT) is often studied in pathological contexts, such as
cancer or fibrosis. This chapter focuses on physiological EMT that allows the separation of …