IL-1 inhibitors in the treatment of monogenic periodic fever syndromes: from the past to the future perspectives

H Malcova, Z Strizova, T Milota, I Striz… - Frontiers in …, 2021 - frontiersin.org
Autoinflammatory diseases (AIDs) represent a rare and heterogeneous group of disorders
characterized by recurrent episodes of inflammation and a broad range of clinical …

Amyloidosis and glomerular diseases in familial Mediterranean fever

R Siligato, G Gembillo, V Calabrese, G Conti… - Medicina, 2021 - mdpi.com
Familial Mediterranean fever (FMF) is a genetic autoinflammatory disease with autosomal
recessive transmission, characterized by periodic fever attacks with self-limited serositis …

A narrative review on the role of cytokines in the pathogenesis and treatment of familial Mediterranean fever: an emphasis on pediatric cases

A Chaaban, H Yassine, R Hammoud, R Kanaan… - Frontiers in …, 2024 - frontiersin.org
Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disease characterized
by an early onset of recurrent fever and serositis episodes. FMF is caused by mutations in …

[HTML][HTML] Rare, overlooked, or underappreciated causes of recurrent Abdominal Pain: a primer for gastroenterologists

DM Brenner, LJ Brandt, M Fenster, MJ Hamilton… - Clinical …, 2023 - Elsevier
Recurrent abdominal pain is a common reason for repeated visits to outpatient clinics and
emergency departments, reflecting a substantial unmet need for timely and accurate …

Efficacy and safety of anti-interleukin-1 treatment in familial Mediterranean fever patients: a systematic review and meta-analysis

B Kilic, Y Guler, FN Azman, E Bostanci… - Rheumatology, 2024 - academic.oup.com
Objectives FMF is the most common hereditary monogenic fever syndrome marked by
recurrent attacks of fever and polyserositis. Colchicine is the current recommended first-line …

Conventional and novel therapeutic options in children with familial Mediterranean fever: A rare autoinflammatory disease

D Poddighe, M Romano… - British journal of …, 2022 - Wiley Online Library
Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory
disease and is usually diagnosed in childhood, especially in the first decade of life …

PREDICT-crFMF score: a novel model for predicting colchicine resistance in children with familial Mediterranean fever

N Aktay Ayaz, FG Demirkan, T Coşkuner… - Modern …, 2024 - academic.oup.com
Objectives To develop a novel scoring system to predict colchicine resistance in Familial
Mediterranean fever (FMF) based on the initial features of the patients. Methods The medical …

The preferential use of anakinra in various settings of FMF: a review applied to an updated treatment-related perspective of the disease

E Giat, I Ben-Zvi, M Lidar, A Livneh - International journal of molecular …, 2022 - mdpi.com
Familial Mediterranean fever (FMF), the most frequent monogenic autoinflammatory
disease, is manifested with recurrent and chronic inflammation and amyloid A (AA) …

Characteristics and course of patients with AA amyloidosis: single centre experience with 174 patients from Turkey

M Bektas, N Koca, E Oguz, S Sari, G Dagci… - …, 2024 - academic.oup.com
Objectives This study aimed to evaluate the clinical, laboratory and genetic characteristics
and outcomes of patients with AA amyloidosis. Methods Patients followed up in a tertiary …

Epigenetic, transcriptional, and functional characterization of myeloid cells in familial Mediterranean fever

RJ Röring, W Li, R Liu, M Bruno, B Zhang… - Iscience, 2024 - cell.com
Familial Mediterranean fever (FMF) is a periodic fever syndrome caused by variation in
MEFV. FMF is known for IL-1β dysregulation, but the innate immune landscape of this …