We live in a world that is largely socially constructed, and we are constantly involved in and
fundamentally influenced by a broad array of complex social interactions. Social behaviors …

Although the etiology and expression of psychiatric disorders are complex, mammals show
biologically preserved behavioral and neurobiological responses to valent stimuli which …

Prairie voles are among a small group of mammals that display long-term social attachment
between mating partners. Many pharmacological studies show that signaling via the …

Unpredictable chronic mild stress (UCMS) is one of the most commonly used, robust and
translatable models for studying the neurobiological basis of major depression. Although the …

Memories are thought to be sparsely encoded in neuronal networks, but little is known about
why a given neuron is recruited or allocated to a particular memory trace. Previous research …

Rodent models of brain disorders including neurodevelopmental, neuropsychiatric, and
neurodegenerative diseases are essential for increasing our understanding of underlying …

The classical studies of nicotine by Langley at the turn of the 20th century introduced the
concept of a “receptive substance,” from which the idea of a “receptor” came to light …

The light/dark test is based on the innate aversion of rodents to brightly illuminated areas
and on the spontaneous exploratory behaviour of rodents in response to mild stressors, that …

Transgenic Tg2576 mice overexpressing human amyloid precursor protein (hAPP) are a
widely used Alzheimer's disease (AD) mouse model to evaluate treatment effects on amyloid …

The open field test (OFT) is a common measure of exploratory behavior and general activity
in both mice and rats, where both the quality and quantity of the activity can be measured …