The prevalence of cerebrovascular disease increases with age, placing the elderly at a
greater lifetime risk for dementia. Vascular cognitive impairment (VCI) encompasses a …

Brain edema is a severe stroke complication that is associated with prolonged
hospitalization and poor outcomes. Swollen tissues in the brain compromise cerebral …

Microglia are the brain's immunocompetent macrophages with a unique feature that allows
surveillance of the surrounding microenvironment and subsequent reactions to tissue …

Following a cerebral ischemic event, substantial alterations in both cellular and molecular
activities occur due to ischemia-induced cerebral pathology. Mounting evidence indicates …

Ischemic stroke occurs when the arteries supplying blood to the brain are narrowed or
blocked, inducing damage to brain tissue due to a lack of blood supply. One effective way to …

Neuroinflammation is a key component of neurological disorders and is an important
therapeutic target; however, immunotherapies have been largely unsuccessful. In cases …

Over the past decades, microbiome research has evolved rapidly and became a hot topic in
basic, preclinical and clinical research, for the pharmaceutical industry and for the general …

Following ischemic stroke, brain‐resident activated microglia and peripherally infiltrated
inflammatory cells create a complicated and overactivated brain immune microenvironment …

It is widely known that ischemic stroke is the prominent cause of death and disability. To
date, neuroinflammation following ischemic stroke represents a complex event, which is an …

Background Monocytes and macrophages are essential components of innate immune
system and have versatile roles in homeostasis and immunity. These phenotypically …