[HTML][HTML] Flavonols as a potential pharmacological intervention for alleviating cognitive decline in diabetes: evidence from preclinical studies

A Horvat, I Vlašić, J Štefulj, N Oršolić… - Life, 2023 - mdpi.com
Diabetes mellitus is a complex metabolic disease associated with reduced synaptic
plasticity, atrophy of the hippocampus, and cognitive decline. Cognitive impairment results …

[HTML][HTML] Altered functional connectivity between brain structures in adults with type 1 diabetes and polyneuropathy

SS Croosu, TM Hansen, B Brock, AM Drewes, C Brock… - Brain Research, 2022 - Elsevier
Objective Alterations of the central nervous system are increasingly being recognized as a
part of diabetes, especially in the thalamus and the default mode network (DMN). However …

[HTML][HTML] Disrupted white matter integrity in the brain of type 1 diabetes is associated with peripheral neuropathy and abnormal brain metabolites

JA Muthulingam, C Brock, TM Hansen… - Journal of Diabetes and …, 2022 - Elsevier
Aims We aimed to quantify microstructural white matter abnormalities using magnetic
resonance imaging and examine their associations with 1) brain metabolite and volumes …

Reduced thalamic volume and metabolites in type 1 diabetes with polyneuropathy

TM Hansen, JB Frøkjær, D Selvarajah… - Experimental and …, 2022 - thieme-connect.com
Objective Thalamus is essential in processing of sensory information. This study explored
the associations between thalamic volume and intra-thalamic metabolites and associations …

[HTML][HTML] Central neuronal transmission in response to tonic cold pain is modulated in people with type 1 diabetes and severe polyneuropathy

EB Mark, D Liao, RB Nedergaard, TM Hansen… - Journal of Diabetes and …, 2022 - Elsevier
Aims This study aimed to investigate cortical source activity and identify source generators in
people with type 1 diabetes during rest and tonic cold pain. Methods Forty-eight participants …

[PDF][PDF] The function of the autonomic nervous system in type 1 diabetes and in response to physiological and pharmacological modulations

TA Nielsen - 2023 - vbn.aau.dk
Type 1 diabetes is a chronic, metabolic disease known to cause microvascular
complications such as retinopathy, neuropathy, and nephropathy. In type 1 diabetes (T1DM) …

Simple quantitative sensory testing reveals paradoxical co-existence of hypoesthesia and hyperalgesia in diabetes

LEM Hansen, CA Fjelsted, SS Olesen… - Frontiers in Pain …, 2021 - frontiersin.org
Background: Diabetic neuropathy is characterized by the paradoxical co-existence of hypo-
and hyperalgesia to sensory stimuli. The literature shows consistently sensory differences …

[PDF][PDF] Multilevel Electrophysiological Methods in Pathophysiolgy and Management: Studies of diabetes, incontinence, and analgesics

RB Nedergaard - 2021 - vbn.aau.dk
As healthcare improves an increasing number of people live longer lives with diseases. As a
result new problems arise that needs to be addressed. Chronic disease brings with it risks of …

Autonomic Visceral Neuropathy and Gastrointestinal Disorders

AM Drewes, C Brock, AM Drewes - The Diabetes Textbook: Clinical …, 2023 - Springer
The brain–gut axis is a bidirectional nexus of the sensory input from the gastrointestinal (GI)
tract and efferent pathways, which is involved in secretion of digestive hormones …