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Regulation of microRNA biogenesis and its crosstalk with other cellular pathways
T Treiber, N Treiber, G Meister - Nature reviews Molecular cell biology, 2019 - nature.com
MicroRNAs (miRNAs) are short non-coding RNAs that inhibit the expression of target genes
by directly binding to their mRNAs. miRNAs are transcribed as precursor molecules, which …
by directly binding to their mRNAs. miRNAs are transcribed as precursor molecules, which …
[HTML][HTML] The non-canonical aspects of microRNAs: many roads to gene regulation
CJ Stavast, SJ Erkeland - Cells, 2019 - mdpi.com
MicroRNAs (miRNAs) are critical regulators of gene expression. As miRNAs are frequently
deregulated in many human diseases, including cancer and immunological disorders, it is …
deregulated in many human diseases, including cancer and immunological disorders, it is …
RNA packaging into extracellular vesicles: An orchestra of RNA‐binding proteins?
Extracellular vesicles (EVs) are heterogeneous membranous particles released from the
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …
MicroRNA in control of gene expression: an overview of nuclear functions
C Catalanotto, C Cogoni, G Zardo - International journal of molecular …, 2016 - mdpi.com
The finding that small non-coding RNAs (ncRNAs) are able to control gene expression in a
sequence specific manner has had a massive impact on biology. Recent improvements in …
sequence specific manner has had a massive impact on biology. Recent improvements in …
Regulation of microRNA biogenesis
M Ha, VN Kim - Nature reviews Molecular cell biology, 2014 - nature.com
MicroRNAs (miRNAs) are small non-coding RNAs that function as guide molecules in RNA
silencing. Targeting most protein-coding transcripts, miRNAs are involved in nearly all …
silencing. Targeting most protein-coding transcripts, miRNAs are involved in nearly all …
Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis
SA Melo, H Sugimoto, JT O'Connell, N Kato… - Cancer cell, 2014 - cell.com
Exosomes are secreted by all cell types and contain proteins and nucleic acids. Here, we
report that breast cancer associated exosomes contain microRNAs (miRNAs) associated …
report that breast cancer associated exosomes contain microRNAs (miRNAs) associated …
Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction
Exosomes are small vesicles that are secreted from metazoan cells and may convey
selected membrane proteins and small RNAs to target cells for the control of cell migration …
selected membrane proteins and small RNAs to target cells for the control of cell migration …
Molecular mechanisms of RNA interference
Small RNA molecules regulate eukaryotic gene expression during development and in
response to stresses including viral infection. Specialized ribonucleases and RNA-binding …
response to stresses including viral infection. Specialized ribonucleases and RNA-binding …
MicroRNA: biogenesis, function and role in cancer
LA MacFarlane, PR Murphy - Current genomics, 2010 - ingentaconnect.com
MicroRNAs are small, highly conserved non-coding RNA molecules involved in the
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
A Cas9–guide RNA complex preorganized for target DNA recognition
Bacterial adaptive immunity uses CRISPR (clustered regularly interspaced short palindromic
repeats)–associated (Cas) proteins together with CRISPR transcripts for foreign DNA …
repeats)–associated (Cas) proteins together with CRISPR transcripts for foreign DNA …