[HTML][HTML] How genomics can help biodiversity conservation

K Theissinger, C Fernandes, G Formenti, I Bista… - Trends in genetics, 2023 - cell.com
The availability of public genomic resources can greatly assist biodiversity assessment,
conservation, and restoration efforts by providing evidence for scientifically informed …

The era of reference genomes in conservation genomics

G Formenti, K Theissinger, C Fernandes, I Bista… - Trends in ecology & …, 2022 - cell.com
Progress in genome sequencing now enables the large-scale generation of reference
genomes. Various international initiatives aim to generate reference genomes representing …

Genetic diversity loss in the Anthropocene

M Exposito-Alonso, TR Booker, L Czech, L Gillespie… - Science, 2022 - science.org
Anthropogenic habitat loss and climate change are reducing species' geographic ranges,
increasing extinction risk and losses of species' genetic diversity. Although preserving …

Leveraging base-pair mammalian constraint to understand genetic variation and human disease

PF Sullivan, JRS Meadows, S Gazal, BDN Phan, X Li… - Science, 2023 - science.org
Thousands of genomic regions have been associated with heritable human diseases, but
attempts to elucidate biological mechanisms are impeded by an inability to discern which …

Multi-omics pipeline and omics-integration approach to decipher plant's abiotic stress tolerance responses

R Roychowdhury, SP Das, A Gupta, P Parihar… - Genes, 2023 - mdpi.com
The present day's ongoing global warming and climate change adversely affect plants
through imposing environmental (abiotic) stresses and disease pressure. The major abiotic …

Chromosomal inversion polymorphisms shape the genomic landscape of deer mice

OS Harringmeyer, HE Hoekstra - Nature Ecology & Evolution, 2022 - nature.com
Chromosomal inversions are an important form of structural variation that can affect
recombination, chromosome structure and fitness. However, because inversions can be …

Genetics of adaptation

K Bomblies, CL Peichel - Proceedings of the National Academy of …, 2022 - pnas.org
The rediscovery of Mendel's work showing that the heredity of phenotypes is controlled by
discrete genes was followed by the reconciliation of Mendelian genetics with evolution by …

Copy number variation introduced by a massive mobile element facilitates global thermal adaptation in a fungal wheat pathogen

SM Tralamazza, E Gluck-Thaler, A Feurtey… - Nature …, 2024 - nature.com
Copy number variation (CNV) can drive rapid evolution in changing environments. In
microbial pathogens, such adaptation is a key factor underpinning epidemics and …

Structural variants and speciation: multiple processes at play

EL Berdan, TG Aubier, S Cozzolino… - Cold Spring …, 2024 - cshperspectives.cshlp.org
Research on the genomic architecture of speciation has increasingly revealed the
importance of structural variants (SVs) that affect the presence, abundance, position, and/or …

Plant pan-genomics comes of age

L Lei, E Goltsman, D Goodstein, GA Wu… - Annual Review of …, 2021 - annualreviews.org
A pan-genome is the nonredundant collection of genes and/or DNA sequences in a species.
Numerous studies have shown that plant pan-genomes are typically much larger than the …