Low-dose IL-2 enhances the generation of IL-10-producing immunoregulatory B cells

A Inaba, ZK Tuong, TX Zhao, AP Stewart… - Nature …, 2023 - nature.com
Dysfunction of interleukin-10 producing regulatory B cells has been associated with the
pathogenesis of autoimmune diseases, but whether regulatory B cells can be therapeutically …

Current advances in the use of bioluminescence assays for drug discovery: An update of the last ten years

MM Calabretta, E Michelini - Expert Opinion on Drug Discovery, 2024 - Taylor & Francis
Introduction Bioluminescence is a well-established optical detection technique widely used
in several bioanalytical applications, including high-throughput and high-content …

BACH2: The Future of Induced T-Regulatory Cell Therapies

D Zwick, MT Vo, YJ Shim, H Reijonen, J Do - Cells, 2024 - mdpi.com
BACH2 (BTB Domain and CNC Homolog 2) is a transcription factor that serves as a central
regulator of immune cell differentiation and function, particularly in T and B lymphocytes. A …