Evolutionary changes in organismal traits may occur either gradually or suddenly. However,
until recently, there has been little direct information about how phenotypic changes are …

Escherichia coli is an important component of the biosphere and is an ideal model for
studies of processes involved in bacterial genome evolution. Sixty-one publically available …

Polyphenol curcumin, a yellow pigment, derived from the rhizomes of a plant (Curcuma
longa Linn) is a natural antioxidant exhibiting a variety of pharmacological activities and …

Conventional wisdom holds that the best way to treat infection with antibiotics is to 'hit early
and hit hard'. A favoured strategy is to deploy two antibiotics that produce a stronger effect in …

Chaperone-usher (CU) fimbriae are adhesive surface organelles common to many Gram-
negative bacteria. Escherichia coli genomes contain a large variety of characterised and …

Escherichia coli ST131 is now recognised as a leading contributor to urinary tract and
bloodstream infections in both community and clinical settings. Here we present the …

Background Escherichia coli is an important species of bacteria that can live as a harmless
inhabitant of the guts of many animals, as a pathogen causing life-threatening conditions or …

The bacterial inactivation mechanisms by solar light and the photo-Fenton process is still a
matter of debate. In this study, we bring evidence towards the elucidation of the mechanisms …

Environmental stresses increase genetic variation in bacteria, plants, and human cancer
cells. The linkage between various environments and mutational outcomes has not been …

There are 29 E. coli genome sequences available, mostly related to studies of species
diversity or mode of pathogenicity, including two genomes of the well-known O157: H7 …