Microbial regulation of organismal energy homeostasis

PD Cani, M Van Hul, C Lefort, C Depommier… - Nature …, 2019‏ - nature.com
The gut microbiome has emerged as a key regulator of host metabolism. Here we review the
various mechanisms through which the gut microbiome influences the energy metabolism of …

Structural brain changes associated with overweight and obesity

E Gómez-Apo, A Mondragón-Maya… - Journal of …, 2021‏ - Wiley Online Library
Obesity is a global health problem with a broad set of comorbidities, such as malnutrition,
metabolic syndrome, diabetes, systemic hypertension, heart failure, and kidney failure. This …

The impact of artificial sweeteners on body weight control and glucose homeostasis

MD Pang, GH Goossens, EE Blaak - Frontiers in nutrition, 2021‏ - frontiersin.org
A poor diet is one of the leading causes for non-communicable diseases. Due to the
increasing prevalence of overweight and obesity, there is a strong focus on dietary …

The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss

A Secher, J Jelsing, AF Baquero… - The Journal of clinical …, 2014‏ - jci.org
Liraglutide is a glucagon-like peptide-1 (GLP-1) analog marketed for the treatment of type 2
diabetes. Besides lowering blood glucose, liraglutide also reduces body weight. It is not fully …

Testosterone and obesity

DM Kelly, TH Jones - Obesity Reviews, 2015‏ - Wiley Online Library
Testosterone is a key hormone in the pathology of metabolic diseases such as obesity. Low
testosterone levels are associated with increased fat mass (particularly central adiposity) …

Mechanisms underlying the weight loss effects of RYGB and SG: similar, yet different

A Pucci, RL Batterham - Journal of endocrinological investigation, 2019‏ - Springer
The worldwide obesity epidemic continues unabated, adversely impacting upon global
health and economies. People with severe obesity suffer the greatest adverse health …

Mood, food, and obesity

M Singh - Frontiers in psychology, 2014‏ - frontiersin.org
Food is a potent natural reward and food intake is a complex process. Reward and
gratification associated with food consumption leads to dopamine (DA) production, which in …

The association between artificial sweeteners and obesity

M Pearlman, J Obert, L Casey - Current gastroenterology reports, 2017‏ - Springer
Abstract Purpose of Review The purpose of this paper is to review the epidemiology of
obesity and the evolution of artificial sweeteners; to examine the latest research on the …

Circulating levels of irisin in patients with anorexia nervosa and different stages of obesity–correlation with body mass index

A Stengel, T Hofmann, M Goebel-Stengel, U Elbelt… - Peptides, 2013‏ - Elsevier
Irisin was recently identified as cleavage product of fibronectin type III domain containing 5
(FNDC5) and shown to increase energy expenditure in mice and humans and therefore was …

The impact of sleep disorders on glucose metabolism: endocrine and molecular mechanisms

A Briançon-Marjollet, M Weiszenstein, M Henri… - Diabetology & metabolic …, 2015‏ - Springer
Modern lifestyle has profoundly modified human sleep habits. Sleep duration has shortened
over recent decades from 8 to 6.5 hours resulting in chronic sleep deprivation. Additionally …