Synthesis and glycosidation of anomeric halides: evolution from early studies to modern methods of the 21st century

Y Singh, SA Geringer, AV Demchenko - Chemical reviews, 2022 - ACS Publications
Advances in synthetic carbohydrate chemistry have dramatically improved access to
common glycans. However, many novel methods still fail to adequately address challenges …

Automated chemical oligosaccharide synthesis: novel approach to traditional challenges

M Panza, SG Pistorio, KJ Stine… - Chemical reviews, 2018 - ACS Publications
Advances in carbohydrate chemistry have certainly made common oligosaccharides much
more accessible. However, many current methods still rely heavily upon specialized …

New principles for glycoside‐bond formation

X Zhu, RR Schmidt - Angewandte Chemie International Edition, 2009 - Wiley Online Library
Meeting the demand for sugars: The importance of oligosaccharides and glycoconjugates in
biological systems has stimulated a need to access significant amounts of these …

Mechanism of chemical O-glycosylation: from early studies to recent discoveries

LK Mydock, AV Demchenko - Organic & biomolecular chemistry, 2010 - pubs.rsc.org
Mechanism of chemical O-glycosylation : from early studies to recent discoveries - Organic &
Biomolecular Chemistry (RSC Publishing) DOI:10.1039/B916088D Royal Society of Chemistry …

Chemical Synthesis of Cell Wall Constituents of Mycobacterium tuberculosis

M Holzheimer, J Buter, AJ Minnaard - Chemical reviews, 2021 - ACS Publications
The pathogen Mycobacterium tuberculosis (Mtb), causing tuberculosis disease, features an
extraordinary thick cell envelope, rich in Mtb-specific lipids, glycolipids, and glycans. These …

Carbohydrates: a frontier in medicinal chemistry

P Stallforth, B Lepenies, A Adibekian… - Journal of medicinal …, 2009 - ACS Publications
Carbohydrates: A Frontier in Medicinal Chemistry | Journal of Medicinal Chemistry Recently
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Synthesis of the docosanasaccharide arabinan domain of mycobacterial arabinogalactan and a proposed octadecasaccharide biosynthetic precursor

M Joe, Y Bai, RC Nacario… - Journal of the American …, 2007 - ACS Publications
Two major components of the cell wall in mycobacteria, including Mycobacterium
tuberculosis, the causative agent of tuberculosis (TB), are polysaccharides containing …

Carbohydrates and immunology: synthetic oligosaccharide antigens for vaccine formulation

L Morelli, L Poletti, L Lay - European journal of organic …, 2011 - Wiley Online Library
Despite the enormous progress achieved by modern medicine, numerous diseases still
have a profound impact on public health. Infectious diseases caused by a variety of …

Recent advances in carbohydrate-based vaccines

ML Hecht, P Stallforth, DV Silva, A Adibekian… - Current opinion in …, 2009 - Elsevier
Vaccinations provide an efficient and cost-effective way to combat devastating human
diseases. Besides pathogenic protein markers, cell surface carbohydrates from biological …

Armed–disarmed effects in carbohydrate chemistry: history, synthetic and mechanistic studies

B Fraser-Reid, JC López - Reactivity Tuning in Oligosaccharide Assembly, 2011 - Springer
This chapter begins with an account of the serendipitous events that led to the development
of n-pentenyl glycosides (NPGs) as glycosyl donors, followed by the chance events that laid …