The role of magnetoencephalography in the early stages of Alzheimer's disease

D López-Sanz, N Serrano, F Maestú - Frontiers in neuroscience, 2018‏ - frontiersin.org
The ever increasing proportion of aged people in modern societies is leading to a
substantial increase in the number of people affected by dementia, and Alzheimer's Disease …

The effects of different acetylcholinesterase inhibitors on EEG patterns in patients with Alzheimer's disease: A systematic review

S Arjmandi-Rad, JD Vestergaard Nieland… - Neurological …, 2024‏ - Springer
Objective Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the
most common type of dementia. The early diagnosis of AD is an important factor for the …

Multimodal classification of Alzheimer's disease and mild cognitive impairment using custom MKSCDDL kernel over CNN with transparent decision-making for …

V Adarsh, GR Gangadharan, U Fiore, P Zanetti - Scientific Reports, 2024‏ - nature.com
The study presents an innovative diagnostic framework that synergises Convolutional
Neural Networks (CNNs) with a Multi-feature Kernel Supervised within-class-similar …

Hypersynchronization in mild cognitive impairment: the 'X'model

S Pusil, ME López, P Cuesta, R Bruna, E Pereda… - Brain, 2019‏ - academic.oup.com
Hypersynchronization has been proposed as a synaptic dysfunction biomarker in the
Alzheimer's disease continuum, reflecting the alteration of the excitation/inhibition balance …

Functional connectivity disruption in subjective cognitive decline and mild cognitive impairment: a common pattern of alterations

D López-Sanz, R Bruña, P Garcés… - Frontiers in aging …, 2017‏ - frontiersin.org
Functional connectivity (FC) alterations represent a key feature in Alzheimer's Disease (AD)
and provide a useful tool to characterize and predict the course of the disease. Those …

[HTML][HTML] Alzheimer's disease disrupts alpha and beta-band resting-state oscillatory network connectivity

L Koelewijn, A Bompas, A Tales, MJ Brookes… - Clinical …, 2017‏ - Elsevier
Abstract Objective Neuroimaging studies in Alzheimer's disease (AD) yield conflicting results
due to selective investigation. We conducted a comprehensive magnetoencephalography …

Neuroplastic effects of combined computerized physical and cognitive training in elderly individuals at risk for dementia: an eLORETA controlled study on resting …

C Styliadis, P Kartsidis, E Paraskevopoulos… - Neural …, 2015‏ - Wiley Online Library
The present study investigates whether a combined cognitive and physical training may
induce changes in the cortical activity as measured via electroencephalogram (EEG) and …

Network disruption and cerebrospinal fluid amyloid-beta and phospho-tau levels in mild cognitive impairment

L Canuet, S Pusil, ME López, R Bajo… - Journal of …, 2015‏ - jneurosci.org
Synaptic dysfunction is a core deficit in Alzheimer's disease, preceding hallmark
pathological abnormalities. Resting-state magnetoencephalography (MEG) was used to …

Sensitive and reproducible MEG resting-state metrics of functional connectivity in Alzheimer's disease

DN Schoonhoven, CT Briels, A Hillebrand… - Alzheimer's Research & …, 2022‏ - Springer
Background Analysis of functional brain networks in Alzheimer's disease (AD) has been
hampered by a lack of reproducible, yet valid metrics of functional connectivity (FC). This …

Alpha band disruption in the AD-continuum starts in the Subjective Cognitive Decline stage: a MEG study

D López-Sanz, R Bruña, P Garcés, C Camara… - Scientific reports, 2016‏ - nature.com
Abstract The consideration of Subjective Cognitive Decline (SCD) as a preclinical stage of
AD remains still a matter of debate. Alpha band alterations represent one of the most …