Flow chemistry involves the use of channels or tubing to conduct a reaction in a continuous
stream rather than in a flask. Flow equipment provides chemists with unique control over …

Reductive amination plays a paramount role in pharmaceutical and medicinal chemistry
owing to its synthetic merits and the ubiquitous presence of amines among biologically …

Hydroformylation is the addition of synthesis gas (“syngas”), a mixture of CO and H2, to
olefins in the presence of a catalyst under the formation of aldehydes. Hydrogen (“hydro”) …

In the context of atom economy and low environmental impact, synthesis of amines by an
efficient catalytic process is of great importance to produce these building blocks for fine …

Catalytic enantiotopic-group-selective cross-couplings of achiral geminal bis
(pinacolboronates) provide a route for the construction of nonracemic chiral …

Carbon–carbon coupling catalyzed by transition metals represents a powerful synthetic
method to have an access to organic molecules, especially when they present a significant …

Enantioselective hydroformylation of alkenes can simultaneously create a new CÀC bond,
install a very versatile functional group, and produces enantiomerically enriched compounds …

Rhodium-catalyzed asymmetric 1, 4-addition of arylboronic acids to coumarins proceeded
with high enantioselectivity in the presence of a rhodium catalyst (3 mol%) generated from …

A continuous flow system for the multiparameter (flow rate, temperature, residence time,
stoichiometry) optimization of the DIBALH reduction of esters to aldehydes is described …

A mild aromatic propargylation reaction, employing an air-and moisture-tolerant rhenium−
oxo complex ((dppm) ReOCl3) as a catalyst and a propargyl alcohol as the electrophile, is …