The effectiveness of anticancer drugs in treating a solid tumour is dependent on delivery of
the drug to virtually all cancer cells in the tumour. The distribution of drug in tumour tissue …

The circadian rhythm is an evolutionarily conserved time-kee** system that comprises a
wide variety of processes including sleep–wake cycles, eating–fasting cycles, and activity …

CONTEXT: Obesity and prostate cancer (PCa) affect substantial proportions of Western
society. Mounting evidence, both epidemiologic and mechanistic, for an association …

Physical exercise has gradually become a focus in cancer treatment due to its pronounced
role in reducing cancer risk, enhancing therapeutic efficacy, and improving prognosis. In …

Cancer is a disease characterized by unrestrained cellular proliferation. In order to sustain
growth, cancer cells undergo a complex metabolic rearrangement characterized by changes …

Importance Men with prostate cancer who are undergoing active surveillance are at an
increased risk of cardiovascular death and disease progression. Exercise has been shown …

Exercise has been shown to improve postischemia perfusion of normal tissues; we
investigated whether these effects extend to solid tumors. Estrogen receptor–negative (ER …

A major objective of the emerging field of exercise–oncology research is to determine the
efficacy of, and biological mechanisms by which, aerobic exercise affects cancer incidence …

Data from observational studies indicate that both physical activity as well as exercise (ie,
structured physical activity) is associated with reductions in the risk of recurrence and cancer …

Background Despite the high global prevalence of prostate cancer (PCa), few epidemiologic
studies have assessed physical activity in relation to PCa survival. Objective To evaluate …